Genetic and Biological Aspects of the HL-A System of Human Histocompatibility [PDF]
J Dausset+4 more
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What's New? Novel immunomodulatory insights derived from experimental models and clinical samples reveal the cancer‐preventive potential of intermittent low‐dose erlotinib plus sulindac (ERL + SUL). This study shows that ERL + SUL treatment upregulates MHC class I and II expression and remodels the immune cell niche, with significant tumor suppression ...
Chakrapani Tripathi+17 more
wiley +1 more source
Polymyositis-Like Myopathy With Anti-PL-12 Antibody Positivity and Coexisting Antiphospholipid Syndrome: Diagnostic and Management Challenges in the Absence of Systemic Features. [PDF]
Parga AD, Raheem I.
europepmc +1 more source
HISTOCOMPATIBILITY-LINKED IMMUNE RESPONSE GENE FUNCTION IN GUINEA PIGS [PDF]
Ethan M. Shevach+2 more
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Engineered strategies for the allergic disease therapy
Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian+4 more
wiley +1 more source
Adenoviral delivery of the CIITA transgene induces T-cell-mediated killing in glioblastoma organoids. [PDF]
Salvato I+13 more
europepmc +1 more source
A germ plasm-transmitted alteration of histocompatibility in the progeny of homograft tolerant mice
Guttmann Rd, J. Bradley Aust
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T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histocompatibility complex-linked immune response genes. [PDF]
A M Solinger+3 more
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Abstract Background Pancreatic cancer remains fatal because of resistance to chemo‐, radio‐, and immunotherapies. Carbon‐ion radiotherapy (CIRT) has been beneficial for patients with pancreatic cancer. The purpose of this study was to identify the mechanism by which CIRT exerts its anticancer activity, particularly in combination with immunotherapy ...
Makoto Sudo+8 more
wiley +1 more source