Results 21 to 30 of about 211,883 (222)

Inferring HIV escape rates from multi-locus genotype data [PDF]

Front. Immunol. 4:252. 2013, 2013
Cytotoxic T-lymphocytes (CTLs) recognize viral protein fragments displayed by major histocompatibility complex (MHC) molecules on the surface of virally infected cells and generate an anti-viral response that can kill the infected cells. Virus variants whose protein fragments are not efficiently presented on infected cells or whose fragments are ...
arxiv   +1 more source

Mesenchymal Stem Cells Inhibit and Stimulate Mixed Lymphocyte Cultures and Mitogenic Responses Independently of the Major Histocompatibility Complex

Scandinavian Journal of Immunology, 2003
We aimed to study the effects of mesenchymal stem cells (MSCs) on alloreactivity and effects of T‐cell activation on human peripheral blood lymphocytes (PBLs) in vitro. MSCs were expanded from the bone marrow of healthy subjects.
K. Blanc, L. Tammik, B. Sundberg, S. Haynesworth, O. Ringdén   +4 more
semanticscholar   +1 more source

Accuracy of Programs for the Determination of Human Leukocyte Antigen Alleles from Next-Generation Sequencing Data

Frontiers in Immunology, 2017
The human leukocyte antigen (HLA) genes code for proteins that play a central role in the function of the immune system by presenting peptide antigens to T cells.
Antti Larjo, Robert Eveleigh, Elina Kilpeläinen, Tony Kwan, Tomi Pastinen, Satu Koskela, Jukka Partanen   +6 more
doaj   +1 more source

The Major Histocompatibility Complex (MHC) in Schizophrenia: A Review

Journal of Clinical & Cellular Immunology, 2016
Epidemiological studies and mouse models suggest that maternal immune activation, induced clinically through prenatal exposure to one of several infectious diseases, is a risk factor in the development of schizophrenia.
Ryan Mokhtari, H. Lachman
semanticscholar   +1 more source

Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry*

Molecular & Cellular Proteomics, 2015
The myriad of peptides presented at the cell surface by class I and class II major histocompatibility complex (MHC) molecules are referred to as the immunopeptidome and are of great importance for basic and translational science.
E. Caron, D. Kowalewski, Ching Chiek Koh, Theo Sturm, H. Schuster, R. Aebersold   +5 more
semanticscholar   +1 more source

False Positive B-Cells Crossmatch after Prior Rituximab Exposure of the Kidney Donor

Case Reports in Transplantation, 2016
Crossmatching is essential prior to kidney transplantation to confirm compatibility between the donor and the recipient, particularly to prevent acute antibody-mediated rejection.
Judith Desoutter, Marie-Joëlle Apithy, Ségolène Bartczak, Nicolas Guillaume   +3 more
doaj   +1 more source

Classical and Non-Classical HLA Alleles as Supplementary Markers in Indirect Kinship Parentage Testing

Immuno, 2022
A civil paternity investigation involving the parents of the deceased alleged father in order to establish a family relationship is presented. On the basis of the 23 autosomal short tandem repeat (aSTR) genotyping results, conclusive proof of paternity ...
Diamanto Kouniaki, Alexandra Tsirogianni
doaj   +1 more source

Influenza and pneumococcal vaccination coverage in Latin American patients with systemic lupus erythematosus: a cross-sectional and comparative study

Advances in Rheumatology, 2021
Background Infections are a major cause of morbidity and mortality in systemic lupus (SLE). Vaccination would be an effective method to reduce infection rate. Coverage for influenza and pneumococcus appears to be low in Latin America.
Edson Hernán Chiganer, Bruno Camargo Ochi, Carmen Flora Lessa   +2 more
doaj   +1 more source

An ontology for major histocompatibility restriction

Journal of Biomedical Semantics, 2016
MHC molecules are a highly diverse family of proteins that play a key role in cellular immune recognition. Over time, different techniques and terminologies have been developed to identify the specific type(s) of MHC molecule involved in a specific ...
R. Vita, James A. Overton, Emily Seymour, J. Sidney, J. Kaufman, R. Tallmadge, S. Ellis, J. Hammond, G. Butcher, A. Sette, Bjoern Peters   +10 more
semanticscholar   +1 more source

Validation of an anti-α-Gal IgE fluoroenzyme-immunoassay for the screening of patients at risk of severe anaphylaxis to cetuximab

BMC Cancer, 2023
Background The link between immediate hypersensitivity reactions (HSR) following the first cetuximab infusion and the IgE sensitization against anti-galactose-α-1,3-galactose (α-Gal) is now well-established.
Julien Serrier, Jean-Baptiste Davy, Benoît Dupont, Bénédicte Clarisse, Jean-Jacques Parienti, Gautier Petit, Kathy Khoy, Yann Ollivier, Radj Gervais, Delphine Mariotte, Brigitte Le Mauff   +10 more
doaj   +1 more source