Results 21 to 30 of about 335,757 (388)

Influenza and pneumococcal vaccination coverage in Latin American patients with systemic lupus erythematosus: a cross-sectional and comparative study

open access: yesAdvances in Rheumatology, 2021
Background Infections are a major cause of morbidity and mortality in systemic lupus (SLE). Vaccination would be an effective method to reduce infection rate. Coverage for influenza and pneumococcus appears to be low in Latin America.
Edson Hernán Chiganer   +2 more
doaj   +1 more source

Phylogenomics and systematics of botryllid ascidians, and implications for the evolution of allorecognition

open access: yesFrontiers in Ecology and Evolution, 2023
Allorecognition, the ability of an organism to distinguish kin from non-kin, or self from non-self, has been studied extensively in a group of invertebrate chordates, the colonial ascidians called botryllids (Subphylum Tunicata, Class Ascidiacea, Family ...
Marie L. Nydam   +9 more
doaj   +1 more source

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products

open access: yesJournal of Experimental Medicine, 1995
We have previously demonstrated that human peripheral blood low density mononuclear cells cultured in granulocyte/macrophage colony-stimulating factor (GM-CSF) and interleukin (IL)-4 develop into dendritic cells (DCs) that are extremely efficient in ...
F. Sallusto   +3 more
semanticscholar   +1 more source

Validation of an anti-α-Gal IgE fluoroenzyme-immunoassay for the screening of patients at risk of severe anaphylaxis to cetuximab

open access: yesBMC Cancer, 2023
Background The link between immediate hypersensitivity reactions (HSR) following the first cetuximab infusion and the IgE sensitization against anti-galactose-α-1,3-galactose (α-Gal) is now well-established.
Julien Serrier   +10 more
doaj   +1 more source

Assessment of Immunological Potential of Glial Restricted Progenitor Graft In Vivo—Is Immunosuppression Mandatory?

open access: yesCells, 2021
Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease, causing motor neuron and skeletal muscle loss and death. One of the promising therapeutic approaches is stem cell graft application into the brain; however, an immune reaction
Urszula Kozlowska   +8 more
doaj   +1 more source

Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation

open access: yesFrontiers in Immunology, 2017
Antigen presentation by major histocompatibility complex (MHC) proteins is essential for adaptive immunity. Prior to presentation, peptides need to be generated from proteins that are either produced by the cell’s own translational machinery or that are ...
M. Wieczorek   +6 more
semanticscholar   +1 more source

Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins [PDF]

open access: yes, 2014
Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. The function of MHC I molecules is to select high affinity peptides from a large intracellular pool and they ...
Bailey, Alistair   +3 more
core   +10 more sources

Bone Marrow Transplantation 1957-2019

open access: yesFrontiers in Immunology, 2019
Clinical bone marrow transplantation started in 1957 at a time when remarkably little was known about hematopoietic stems cells, immune responses to transplants or the identity of transplant antigens.
Elizabeth Simpson, Francesco Dazzi
doaj   +1 more source

Highly Sensitized Patients Are Well Served by Receiving a Compatible Organ Offer Based on Acceptable Mismatches

open access: yesFrontiers in Immunology, 2021
Highly sensitized kidney patients accrue on the transplant waiting list due to their broad immunization against non-self Human Leucocyte Antigens (HLA).
Sebastiaan Heidt   +3 more
doaj   +1 more source

Biocompatibility of polyetheretherketone for the treatment of orbital bone defects [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To investigate the biocompatibility and therapeutic effects of polyetheretherketone (PEEK) on recovery of a rabbit orbital defect. METHODS: Totally 16 New Zealand rabbits were used to establish an orbital bone defect model and then randomly divided
Rui-Dong Gu   +4 more
doaj   +1 more source

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