Results 131 to 140 of about 64,134 (148)
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Presentation of Exogenous Antigen with Class I Major Histocompatibility Complex Molecules
Science, 1990Soluble antigens (Ags) in the extracellular fluids are excluded from the class I major histocompatibility complex (MHC)-restricted pathway of Ag presentation in most cells. However, an exogenous Ag can be internalized, processed, and presented in association with class I MHC molecules on specialized Ag-presenting cells (APCs).
K L, Rock, S, Gamble, L, Rothstein
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Major Histocompatibility Complex Class I Antigens Expressed on Rat Trophoblast Cells
American Journal of Reproductive Immunology, 1990ABSTRACT: There is controversy about the size of the major histocompatibility complex antigens of trophoblast cells from placenta. There are some reports that the heavy chains of these molecules are smaller (39–43 kd) than those of the classical class I antigens (45–46 kd), while there are others which show that both the light and the heavy forms of ...
M, Saito +3 more
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Invasive equine trophoblast expresses conventional class I Major Histocompatibility Complex antigens
Development, 1990Abstract Monoclonal antibodies and alloantisera were used in an indirect immunohistochemical assay to determine the expression of class I and class II Major Histocompatibility Complex (MHC) antigens by equine placental cells and the endometrial tissues at the fetal-maternal interface.
W L, Donaldson +3 more
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ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX
Annual Review of Immunology, 1996▪ Abstract Major histocompatibility complex (MHC) class I molecules bind peptides derived from cellular proteins and display them for surveillance by the immune system. These peptide-binding molecules are composed of a heavy chain, containing an antigen-binding groove, which is tightly associated with a light chain (β2-microglobulin).
I A, York, K L, Rock
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Beta-2-Microglobulin of Rat Major Histocompatibility Complex Class I Antigens
International Archives of Allergy and Immunology, 1989Detection of the β<sub>2</sub>-microglobulin (β<sub>2</sub>m) component of the rat MHC class I antigens has been difficult. In the present report, we have addressed this issue by a systematic study of rat class I antigens from red blood cells or from lymphocytes that were freshly isolated or cultured in the presence of ...
D N, Misra, H W, Kunz, T J, Gill
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Expression of class I and class II major histocompatibility complex antigens on human hepatocytes
Hepatology, 1988We analyzed whether normal human hepatocytes, which normally do not display Class II major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases.
A. Franco +5 more
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IgG Fe receptors that resemble class I major histocompatibility complex antigens
Biochemical Society Transactions, 1993(1) The intestinal Fc receptors of neonatal rats and mice consists of beta 2m and an alpha-chain that is similar to those of MHC class I and CD1 antigens. (2) Mouse and rat FcRns are highly conserved. There are no amino acid substitutions in the 90 amino acid alpha 3 domain, and only one in the 40 amino acid cytoplasmic tail. (3) Despite its similarity
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Biochemical characterization of human Class I histocompatibility antigens
Immunology Letters, 1997J.M. Escolano +6 more
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Are Medial Class I Histocompatibility Antigens Coming of Age?
1993The major histocompatibility complex (MHC) encodes one to three classical class I, or class Ia, molecules. These are expressed in all tissues at relatively high levels, present endogenous minor histocompatibility antigens and foreign viral antigens on the cell surface, and are usually highly polymorphic.
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HLA Class I Histocompatibility Antigen, Alpha Chain E
2016Alexander A. Celik +2 more
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