Results 261 to 270 of about 112,304 (310)

Molecular Mechanism for the Selective Presentation of Antigenic Peptides by Major Histocompatibility Complex Class I and Class II Molecules: A Hypothesis. [PDF]

Curr Issues Mol Biol
Zhu BT.
europepmc   +1 more source

T-cell receptor insights: Determinants of Major Histocompatibility Complex class I versus class II recognition. [PDF]

Protein Sci
De Almeida Mendes M, Chihab L, Nilsson JB, Scheffer L, Nielsen M, Peters B.   +5 more
europepmc   +1 more source

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Tolerance of class I histocompatibility antigens expressed extrathymically

Nature, 1989
Although convincing evidence has been obtained for the imposition of self-tolerance by the intrathymic deletion of self-reactive T cells, the development of tolerance to antigens which are expressed only in the periphery is not so well understood.
G, Morahan, J, Allison, J F, Miller
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Molecules Related To Class-I Major Histocompatibility Complex Antigens

Annual Review of Immunology, 1990
Article de synthese sur la structure et l'expression de molecules apparentees aux molecules de classe I chez la souris. Etat de la recherche sur les molecules solubles, liees a des phospholipides et membranaires comprises dans ce groupe; etude comparative des structures de ces ...
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Structure of the human class I histocompatibility antigen, HLA-A2

Nature, 1987
The class I histocompatibility antigen from human cell membranes has two structural motifs: the membrane-proximal end of the glycoprotein contains two domains with immunoglobulin-folds that are paired in a novel manner, and the region distal from the membrane is a platform of eight antiparallel beta-strands topped by alpha-helices.
P J, Bjorkman, M A, Saper, B, Samraoui, W S, Bennett, J L, Strominger, D C, Wiley   +5 more
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Subunit interactions of class I histocompatibility antigens

Biochemistry, 1985
The kinetics of dissociation of iodinated beta 2-microglobulin (beta 2m) from the papain-solubilized class I histocompatibility antigen HLA-B7 have been investigated. In the presence of unlabeled beta 2m, most of the HLA dissociates according to a single rate constant, whereas in the absence of unlabeled beta 2m, the system approaches an equilibrium ...
K C, Parker, J L, Strominger
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Proteolysis and class I major histocompatibility complex antigen presentation

Immunological Reviews, 1999
Summary: The class I major histocompatibility complex (MHC class 1) presents 8–10 residue peptides to cytotoxic T lymphocytes. Most of these antigenic peptides are generated during protein degradation in the cytoplasm and are then transported into the endoplasmic reticulum by the transporter associated with antigen processing (TAP), Several lines of ...
I A, York, A L, Goldberg, X Y, Mo, K L, Rock   +3 more
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Structure of Class I Major Histocompatibility Antigens

1983
H-2 antigens were discovered by Gorer (1936) as a blood group system associated with histocompatibility between mouse strains. Later research indicated that H-2 antigens were encoded by a series of genes, hence the designation H-2 complex (J. Klein, 1975).
E S, Kimball, J E, Coligan
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