Results 51 to 60 of about 112,304 (310)

Expression of CD163 and major histocompatibility complex class I as diagnostic markers for idiopathic inflammatory myopathies

Arthritis Research & Therapy
Background To develop an inflammation-related immunohistochemistry marker-based algorithm that confers higher diagnostic ability for idiopathic inflammatory myopathies (IIMs) than IIM-related histopathologic features.
Byeongzu Ghang, So Hye Nam, Wonho Choi, Hwa Jung Kim, Jungsun Lee, Doo-Ho Lim, Soo Min Ahn, Ji Seon Oh, Seokchan Hong, Yong-Gil Kim, Chang-Keun Lee, Jinseok Kim, Bin Yoo, Soo Jeong Nam   +13 more
doaj   +1 more source

Comparison of exon 5 sequences from 35 class I genes of the BALB/c mouse [PDF]

, 1989
DNA sequences of the fifth exon, which encodes the transmembrane domain, were determined for the BALB/c mouse class I MHC genes and used to study the relationships between them. Based on nucleotide sequence similarity, the exon 5 sequences can be divided
Brorson, Kurt A., Cheroutre, Hilde, Hood, Leroy, Hunkapiller, Tim, Hunt, Stephen W., III, Nickerson, Deborah A., Sun, Y. Henry   +6 more
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules

Frontiers in Immunology, 2023
Major Histocompatibility Complex class I (MHC-I) molecules display self, viral or aberrant epitopic peptides to T cell receptors (TCRs), which employ interactions between complementarity-determining regions with both peptide and MHC-I heavy chain ...
Georgia F. Papadaki, Georgia F. Papadaki, Omar Ani, Tyler J. Florio, Tyler J. Florio, Michael C. Young, Michael C. Young, Julia N. Danon, Julia N. Danon, Yi Sun, Yi Sun, Devin Dersh, Nikolaos G. Sgourakis, Nikolaos G. Sgourakis   +13 more
doaj   +1 more source

Major Histocompatibility Complex I and II Expression and Lymphocytic Subtypes in Muscle of Horses with Immune-Mediated Myositis. [PDF]

, 2016
BackgroundMajor histocompatibility complex (MHC) I and II expression is not normally detected on sarcolemma, but is detected with lymphocytic infiltrates in immune-mediated myositis (IMM) of humans and dogs and in dysferlin-deficient muscular dystrophy ...
Barnes, N, Durward-Akhurst, SA, Finno, CJ, Guo, LT, Shelton, GD, Shivers, J, Valberg, SJ   +6 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Antigen processing for MHC class II presentation via autophagy

Frontiers in Immunology, 2012
T cells recognize proteolytic fragments of antigens that are presented to them on major histocompatibility complex (MHC) molecules. MHC class I molecules present primarily products of proteasomal proteolysis to CD8+ T cells, while MHC class II molecules ...
Christian eMunz
doaj   +1 more source

HLA‐A*24:02 increase the risk of allopurinol‐induced drug reaction with eosinophilia and systemic symptoms in HLA‐B*58:01 carriers in a Korean population; a multicenter cross‐sectional case‐control study

Clinical and Translational Allergy, 2022
Background HLA‐B*58:01 is a well‐known risk factor for allopurinol‐induced severe cutaneous adverse reactions (SCARs). However, only a minority of HLA‐B*58:01 carriers suffer SCARs after taking allopurinol.
Mi‐Yeong Kim, James Yun, Dong‐Yoon Kang, Tae Hee Kim, Min‐Kyung Oh, Sunggun Lee, Min‐Gyu Kang, Young‐Hee Nam, Jeong‐Hee Choi, Min‐Suk Yang, Seung Seok Han, Hajeong Lee, Hyun‐Jai Cho, Jaeseok Yang, Kook‐Hwan Oh, Yon Su Kim, Jae Woo Jung, Kye Hwa Lee, Hye‐Ryun Kang   +18 more
doaj   +1 more source

Natural Killer Cells in Antibody Independent and Antibody Dependent HIV Control

Frontiers in Immunology, 2022
Infection with the human immunodeficiency virus (HIV), when left untreated, typically leads to disease progression towards acquired immunodeficiency syndrome.
Nicole F. Bernard, Nicole F. Bernard, Nicole F. Bernard, Nicole F. Bernard, Sanket Kant, Sanket Kant, Sanket Kant, Zahra Kiani, Zahra Kiani, Zahra Kiani, Cécile Tremblay, Cécile Tremblay, Franck P. Dupuy, Franck P. Dupuy   +13 more
doaj   +1 more source

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4. [PDF]

, 1985
Autoimmune NZB/NZW mice were treated with weekly injections of monoclonal antibody (mAb) to L3T4, an antigen expressed on a distinct subpopulation of T cells that respond to class II major histocompatibility antigens.
Seaman, WE, Wofsy, D
core   +1 more source