Results 31 to 40 of about 23,603,276 (341)

Dendritic cells crosspresent antigens from live B16 cells more efficiently than from apoptotic cells and protect from melanoma in a therapeutic model. [PDF]

PLoS ONE, 2011
Dendritic cells (DC) are able to elicit anti-tumoral CD8(+) T cell responses by cross-presenting exogenous antigens in association with major histocompatibility complex (MHC) class I molecules.
Diana Matheoud, Camille Baey, Lene Vimeux, Andy Tempez, Michael Valente, Pauline Louche, Agnès Le Bon, Anne Hosmalin, Vincent Feuillet   +8 more
doaj   +1 more source

Escape from the phagosome: the explanation for MHC-I processing of mycobacterial antigens?

Frontiers in Immunology, 2012
Mycobacterium tuberculosis (Mtb) is thought to live in an altered phagosomal environment. In this setting, the mechanisms by which mycobacterial antigens access the major histocompatibility class I (MHC-I) processing machinery remain incompletely ...
Melanie eHarriff, Melanie eHarriff, Georgiana ePurdy, David M Lewinsohn, David M Lewinsohn, David M Lewinsohn   +5 more
doaj   +1 more source

Differential phosphorylation of murine class I major histocompatibility antigens

Bioscience Reports, 1988
Recent studies have shown that the H-2K and H-2D transplantation antigens are expressed differentially in different tissues of mouse. Our previous investigations also established that in thioglycolate-stimulated peritoneal macrophages the H-2Dk antigen exists in distinct cell surface and intracellular forms. These two forms are glycosylated differently.
W J, Hong, A, Van Le, D, Doyle
openaire   +2 more sources

Sequence of the mouse Q4 class I gene and characterization of the gene product [PDF]

, 1988
The Q4 class I gene has been shown to participate in gene conversion events within the mouse major histocompatibility complex. Its complete genomic nucleotide sequence has been determined.
Robinson, Peter J., Bevec, Dorian, Mellor, Andrew L., Weiss, Elisabeth H.   +3 more
core   +1 more source

Serum Levels of Classical HLA Class I Antigen in HIV-Infected patients during antiretroviral therapy. Correlation with the clinical outcome

Journal of Biological Research, 2009
Aim. Human major histocompatibility complex class I antigens (HLA-A, -B, and -C) are heterodimetric molecules composed of a heavy chain non covalently associated with an invariant protein known as B2-microglobulin. Besides being expressed on the membrane
G. Murdaca, P. Cagnati, F. Puppo
doaj   +1 more source

Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex

Emerging Infectious Diseases, 1997
Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
doaj   +1 more source

A peptide filtering relation quantifies MHC class I peptide optimization [PDF]

, 2011
Major Histocompatibility Complex (MHC) class I molecules enable cytotoxic T lymphocytes to destroy virus-infected or cancerous cells, thereby preventing disease progression. MHC class I molecules provide a snapshot of the contents of a cell by binding to
Luca Cardelli, Goldstein, LD, Phillips, Andrew, Emmott, Stephen, Elliott, T, Mark Howarth, Werner, JM, Werner, Joern M., Leonard D. Goldstein, Andrew Phillips, Elliot, Tim, Dalchau, Neil, Goldstein, Leonard D., Cardelli, L, Cardelli, Luca, Tim Elliott, Dalchau, N, Emmott, S, Neil Dalchau, Howarth, M, Elliott, Tim, Leonard D Goldstein, Joern M. Werner, Phillips, A, Joern M Werner, Stephen Emmott, Howarth, Mark   +26 more
core   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

Arquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN, Sinan SARI, Yaşar KANDUR, Buket DALGIÇ, Oğuz SÖYLEMEZOĞLU   +4 more
doaj   +1 more source

Enhanced Expression of Interferon-γ-Induced Antigen-Processing Machinery Components in a Spontaneously Occurring Cancer

Neoplasia: An International Journal for Oncology Research, 2007
In human tumors, changes in the surface expression and/or function of major histocompatibility complex (MHC) class I antigens are frequently found and may provide malignant cells with a mechanism to escape control of the immune system. This altered human
Fulvia Cerruti, Marina Martano, Claudio Petterino, Enrico Bollo, Emanuela Morello, Renato Bruno, Paolo Buracco, Paolo Cascio   +7 more
doaj   +1 more source

E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]

, 2005
Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara, O'Brien, P.M., Ashrafi, G. Hossein, Haghshenas, Mohammad R., O'Brien, Philippa M., Ashrafi, G.H., Haghshenas, M.R., Campo, M.S., Marchetti, B., Campo, M. Saveria   +9 more
core   +1 more source