Results 21 to 30 of about 68,749 (310)

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

open access: yeseLife, 2018
Devil Facial Tumour 2 (DFT2) is a recently discovered contagious cancer circulating in the Tasmanian devil (Sarcophilus harrisii), a species which already harbours a more widespread contagious cancer, Devil Facial Tumour 1 (DFT1).
Alison Caldwell   +13 more
doaj   +1 more source

Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein [PDF]

open access: yes, 1992
Computer simulation of the conformations of short antigenic peptides (&lo residues) either free or bound to their receptor, the major histocompatibility complex (MHC)- encoded glycoprotein H-2 Ld, was employed to explain experimentally determined ...
Reddehase, Matthias J.   +7 more
core   +1 more source

Manipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Major histocompatibility complex (MHC) antigens are important for alloimmune responses as well as immune tolerance. Previous studies have shown that presentation of donor MHC antigens by donor-specific transfusion prior to or upon ...
Shuzi Zhang   +4 more
doaj   +1 more source

Major histocompatibility class I antigens in the Lebanese population

open access: yesEastern Mediterranean Health Journal, 2021
Except for two reports on Lebanese immigrants, there have been no studies on the major histocompatibility [MHC] antigens in the Lebanese population. We describe the frequency and distribution of MHC class I antigens present in the A, B and C loci based on data obtained from 200 healthy unrelated individuals from different parts of Lebanon.
N. N. Salti, M. Shaya
openaire   +1 more source

Sequence of the mouse Q4 class I gene and characterization of the gene product [PDF]

open access: yes, 1988
The Q4 class I gene has been shown to participate in gene conversion events within the mouse major histocompatibility complex. Its complete genomic nucleotide sequence has been determined.
Robinson, Peter J.   +3 more
core   +1 more source

Escape from the phagosome: the explanation for MHC-I processing of mycobacterial antigens?

open access: yesFrontiers in Immunology, 2012
Mycobacterium tuberculosis (Mtb) is thought to live in an altered phagosomal environment. In this setting, the mechanisms by which mycobacterial antigens access the major histocompatibility class I (MHC-I) processing machinery remain incompletely ...
Melanie eHarriff   +5 more
doaj   +1 more source

Dendritic cells crosspresent antigens from live B16 cells more efficiently than from apoptotic cells and protect from melanoma in a therapeutic model. [PDF]

open access: yesPLoS ONE, 2011
Dendritic cells (DC) are able to elicit anti-tumoral CD8(+) T cell responses by cross-presenting exogenous antigens in association with major histocompatibility complex (MHC) class I molecules.
Diana Matheoud   +8 more
doaj   +1 more source

Differential phosphorylation of murine class I major histocompatibility antigens

open access: yesBioscience Reports, 1988
Recent studies have shown that the H-2K and H-2D transplantation antigens are expressed differentially in different tissues of mouse. Our previous investigations also established that in thioglycolate-stimulated peritoneal macrophages the H-2Dk antigen exists in distinct cell surface and intracellular forms. These two forms are glycosylated differently.
W J, Hong, A, Van Le, D, Doyle
openaire   +2 more sources

Serum Levels of Classical HLA Class I Antigen in HIV-Infected patients during antiretroviral therapy. Correlation with the clinical outcome

open access: yesJournal of Biological Research, 2009
Aim. Human major histocompatibility complex class I antigens (HLA-A, -B, and -C) are heterodimetric molecules composed of a heavy chain non covalently associated with an invariant protein known as B2-microglobulin. Besides being expressed on the membrane
G. Murdaca, P. Cagnati, F. Puppo
doaj   +1 more source

Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex

open access: yesEmerging Infectious Diseases, 1997
Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
doaj   +1 more source

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