Results 151 to 160 of about 108,384 (342)

Regulation of T cell response to leishmania antigens by determinants of histocompatibility leukocyte class I and II molecules

open access: yesBrazilian Journal of Medical and Biological Research, 1998
It has been shown that HLA class I molecules play a significant role in the regulation of the proliferation of T cells activated by mitogens and antigens.
Bacellar O., Russo C., Carvalho E.M.
doaj  

Transition from psoriasis to psoriatic arthritis is characterized by distinct alterations in peripheral blood Tc17, Th17 and CD4+ TEM cells

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff   +19 more
wiley   +1 more source

Canine intestinal organoids as a platform for studying MHC class II expression in epithelial cells

open access: yesBMC Molecular and Cell Biology
Backgrounds The interplay between intestinal epithelial cells (IECs), the immune system, and the gut microbiome is pivotal for maintaining gastrointestinal homeostasis and mediating responses to ingested antigens.
Meg Nakazawa   +2 more
doaj   +1 more source

Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. Variable copy number (CN) of C4 genes and retroviral HERV‐K element influence its function.
Javier Martínez‐López   +23 more
wiley   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

open access: yesBMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang   +7 more
wiley   +1 more source

CARDIAC TRANSPLANTATION IN THE RAT [PDF]

open access: yes, 1989
CHAPMAN, FRANCES A   +6 more
core   +1 more source

Amino acid polymorphisms in human histocompatibility leukocyte antigen class II and proinsulin epitope have impacts on type 1 diabetes mellitus induced by immune-checkpoint inhibitors

open access: gold, 2023
Hidefumi Inaba   +17 more
openalex   +1 more source

Home - About - Disclaimer - Privacy