Results 201 to 210 of about 8,473,299 (309)

Detection of RBC-bound antibodies using flow cytometry and their correlation with HLA polymorphism. [PDF]

Front Immunol
Ullah A, Liu L, Qi X, Liu H.
europepmc   +1 more source

HLA Class II Histocompatibility Antigen, DM Alpha Chain [PDF]

, 2020
openaire   +1 more source

From haemostasis to immunity: The expanding frontiers of platelet biology

British Journal of Haematology, EarlyView.
Platelets are versatile cells whose functions extend far beyond haemostasis and thrombosis, actively regulating innate and adaptive immunity, angiogenesis, lymphangiogenesis, liver regeneration, atherosclerosis and tumour metastasis. This demonstrates their central role in various physiological processes and multiple life‐threatening diseases ...
Xun Grace Wu, Nicole Tomei, Heyu Ni
wiley   +1 more source

The Role of Chimeric Antigen Receptor Regulatory T Cells in Promoting Immune Tolerance in Solid Organ Transplantation: <i>Mechanisms and Therapeutic Potential</i>. [PDF]

Saudi Med J
Alwethaynani MS.
europepmc   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Clinical applications and methodology updates in HLA typing. [PDF]

BMC Immunol
Feng K, Chang L, Yan Y, Sun H, Liu Y, Song S, Nuermaimaiti A, Halemubieke S, Mei L, Su Q, Liu X, Lu Z, Ji H, Wang L.   +13 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Correlation between recognition of autologous tumor organoids by tumor-infiltrating lymphocytes from metastatic epithelial cancers and clinical response. [PDF]

J Immunother Cancer
Gustafson AM, Bhasin A, Gasmi B, Bui BD, Ade CM, Hanada KI, Halas HK, Gartner JJ, Prickett TD, Salazar J, Parkhust MR, Robbins P, Klemen ND, Kwong ML, Goff SL, Rosenberg SA, Yang JC.   +16 more
europepmc   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

HLA Class I Loss and Resistance to Immunotherapy in Pulmonary Metastasis of Hypopharyngeal Cancer. [PDF]

In Vivo
Murakami A, Yukino K, Komohara Y, Shimoda YU, Saito H, Fujiwara Y, Orita Y.   +6 more
europepmc   +1 more source