Preformed <i>vs de novo</i> anti-human leukocyte antigens-DQ antibodies in kidney transplantation: A retrospective study. [PDF]
Guissouss O +9 more
europepmc +1 more source
Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
Enterocyte Autoantibodies (GECAs) and HLA: Their Relationship with HIV Infection Pathogenesis. [PDF]
Arnaiz-Villena A +4 more
europepmc +1 more source
HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein [PDF]
openaire +1 more source
Genomic and proteomic insights into hidradenitis suppurativa
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou +8 more
wiley +1 more source
The organ transplanted patient - immunological concepts and immunosuppression [PDF]
Husberg, BS, Klintmalm, GBG, Starzl, TE
core
MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-ASSOCIATED VACCINE PROTECTION FROM SIMIAN IMMUNODEFICIENCY VIRUS-INFECTED PERIPHERAL-BLOOD CELLS [PDF]
Boes, J +14 more
core +1 more source
ABSTRACT Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, accounting for up to 80% of all cases. Most patients present at an advanced stage and are unsuitable for curative treatments. In the past 5 years, immunotherapy combination has superseded tyrosine kinase inhibitors (TKI) as the standard first‐line therapy for ...
Landon L. Chan +2 more
wiley +1 more source
Rapamycin-modified novel tolerogenic dendritic cells induce liver graft tolerance through MHC-II+CD8+ regulatory T cells. [PDF]
Zhou L +11 more
europepmc +1 more source
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed +6 more
wiley +1 more source

