Allelic variation in the TNF-beta gene does not explain the low TNF-beta response in patients with primary biliary cirrhosis [PDF]
Eisenburg, Josef +19 more
core +1 more source
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Summary Immune thrombocytopenia (ITP) is a complex autoimmune disorder characterized by accelerated destruction of peripheral platelets and impaired megakaryopoiesis. While the cellular effectors, dysregulated T cells, hyperactive B cells and phagocytic macrophages are well characterized, the upstream epigenetic mechanisms orchestrating this ...
Zhenyu Liu +8 more
wiley +1 more source
Oligoprogressive renal cell carcinoma: What is the role of surgery?
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re +9 more
wiley +1 more source
Mixed Lymphocyte Reaction: Functional Immune Profiling in Transplantation and Beyond. [PDF]
Galimov N +3 more
europepmc +1 more source
Reimbursement for Organ Procurement and Histocompatibility Testing and for Home Dialysis Equipment
core
The Novel HLA Class II Alleles DRB1*15:03:06, DQB1*03:01:69 and DPB1*04:01:95 Identified in Brazilian Donors. [PDF]
Dos Santos Júnior ACS +4 more
europepmc +1 more source
Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
wiley +1 more source
Human leukocyte antigen-incompatible living donor kidney transplantation after desensitization: experience from a major transplant centre in Mexico. [PDF]
Reynoso de la Torre HL +19 more
europepmc +1 more source
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen +5 more
wiley +1 more source

