Results 161 to 170 of about 18,790,944 (322)

Clinical Histocompatibility Testing [PDF]

Journal of Clinical Pathology, 1981
openaire   +1 more source

Reducing Early Graft Loss in Xenotransplantation With Histocompatibility Testing. [PDF]

Transplantation
Tector M, Tector AJ.
europepmc   +1 more source

SERPINB9 Promotes Colorectal Cancer Liver Metastasis and Immunotherapy Resistance: Association With MHC‐I Downregulation and CD8+ T Cell Dysfunction

Medicine Bulletin, EarlyView.
ABSTRACT Background Colorectal cancer liver metastasis (CRLM) is the leading cause of mortality in colorectal cancer (CRC) patients, for which effective treatments remain limited. The mechanisms by which tumor cells evade immune surveillance and escape cytotoxic killing remain poorly understood.
Xin Liu, Wenchen Wang, Hongqian Wang, Yanshen Kuang, Baoqing Jia   +4 more
wiley   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Primary or secondary sicca complex? Investigation in primary biliary cirrhosis by histocompatibility testing.

British medical journal, 1980
A. Hamlyn, D. Adams, S. Sherlock
semanticscholar   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

Immunomodulatory, Antibacterial, Antioxidative and EGF‐Delivering Hydrogel Remodels Wound Microenvironment for Infected Diabetic Wound Healing

National Materials, EarlyView.
In this study, we engineered an antibacterial, antioxidative and epidermal grow factor‐encapsulated multifunctional hydrogel for the repair of chronic and refractory wounds. The hydrogel markedly promoted wound healing in rat models of diabetic foot ulcers and infected wounds by modulating wound microenvironment.
Zheng Zou, Yang Gao, Desheng Qi, Zhen Zhang, Chaoliang He, Xuesi Chen   +5 more
wiley   +1 more source

ISOT Position Statement on Immunological Evaluation in Kidney Transplantation. [PDF]

Clin Transplant
Balwani MR, Kumar A, Kute VB, Saxena K, Kashiv P, Shrimali J, Banerjee S, Engineer DP, Agarwal SK, Kolte S, Pasari A, Aziz F, Das P, Hegde U, Ray DS, Agarwal D, Sharma S, Bhawane A, Prasad N, Chaudhury AR, Raju S, Tapiawala S, Jain V, Das D, Deshpande V, Ramteke V, Sharma A, Bhalla AK, Guleria S, Abraham G, Parmar V, Selvakumar S, Godara SM, Gothwal K, Chauhan S, Meshram HS.   +35 more
europepmc   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

BeadWatch: Automated Longitudinal Quality Control Monitoring for Luminex Bead-Based Immunoassays in Histocompatibility Laboratories. [PDF]

HLA
Chen M, Docker H, Williams D, Cutland G, Costa MQ, Barnardo MCN.   +5 more
europepmc   +1 more source