Results 181 to 190 of about 18,790,944 (322)

A prospective study of histocompatibility testing for keratoplasty in high-risk patients.

British Journal of Ophthalmology, 1986
O. Ozdemir
semanticscholar   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Characterisation of the MICA*045:01:04 and MICA*004:01:22 Alleles in Haematopoietic Stem Cell Donors From India. [PDF]

HLA
Agarwal D, Sharma G, Khadwal A, Malhotra P.   +3 more
europepmc   +1 more source

Genomic Assessment of Reintroduced African Wild Dogs Informs Conservation Translocations

Animal Conservation, EarlyView.
Few reintroduction and translocation programs incorporate genomic assessments into management planning, despite ongoing debate over how founder individuals should be selected. Here, we assess the genomic composition of reintroduced African wild dog (Lycaon pictus) populations in private reserves in South Africa, comparing them with a free‐roaming ...
Michou Weimar, Cole du Plessis, Rosemary Groom, Bettine Jansen van Vuuren, Laura Tensen   +4 more
wiley   +1 more source

Genomic Confirmation of HLA-DPA1*01:49 by Next Generation Sequencing and Oxford Nanopore Sequencing. [PDF]

HLA
Merschman J, Kreuter J, Wakefield L, Gandhi MJ.   +3 more
europepmc   +1 more source

Evidence for Reduced Somatic T‐Cell Receptor Sequence Diversity Profiles Among Midwestern Amish in an Aging Cohort Study

Annals of Human Genetics, EarlyView.
ABSTRACT Background The causes of late onset Alzheimer disease (LOAD) are not known but several recent lines of evidence implicate the adaptive immune system. Objective To characterize the adaptive immune system among Midwestern Amish participating in longitudinal studies of aging.
Lauren A. Cruz, Shiying Liu, Kristy L. Miskimen, Jessica N. Cooke Bailey, Tyler Kinzy, Yeunjoo E. Song, Renee A. Laux, Penelope Miron, Paula K. Ogrocki, Alan J. Lerner, Audrey Lynn, Sarada L. Fuzzell, Sherri D. Hochstetler, Ioanna Konidari, Jacob L. McCauley, William K. Scott, Margaret A. Pericak‐Vance, Jonathan L. Haines, Dana C. Crawford   +18 more
wiley   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Editorial: Proficiency testing in histocompatibility and immunogenetics: current status and future perspectives

Frontiers in Genetics
Martin Petrek, Martin Petrek, Kelley M. K. Hitchman, Kelley M. K. Hitchman, Kelley M. K. Hitchman   +4 more
doaj   +1 more source

Recommendations From the Implementation Steering Group for Organ Utilisation Histocompatibility and Immunogenetics Sub-Group: ISOU H&I Sub-Group Recommendations. [PDF]

Int J Immunogenet
Speirs NC, Chalker V, Clark B, Courtney AE, Daga S, Griffin S, Kallon D, Kim JJ, Kosmoliaptsis V, Latham K, Peacock S, Shaw O, Nieto T, Ravanan R, Battle R.   +14 more
europepmc   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source