Results 61 to 70 of about 82,500 (201)

Origin of lymph node-derived lymphocytes in human hepatic allografts [PDF]

, 1989
Hepatic allograft-derived lymph nodes were examined in the post-transplant period on order to determine the origin of lymphocytes and structural elements of the lymph node.
Chen, K, Demetris, AJ, Duquesnoy, RJ, Fung, JJ, Markus, B, Marrarri, M, Starzl, TE, Zeevi, A   +7 more
core   +1 more source

Angiotensin II Type-1 Receptor Antibody in Solid Organ Transplantation – Is It Time to Test?

Transplant International
Angiotensin II type-1 receptor antibody (AT1R-Ab) has been mooted as a potential effector of both acute and chronic antibody mediated rejection (AMR). A growing body of literature on the topic is now coming under scrutiny in the context of the evolving ...
Paul James Patrick Martin, Paul James Patrick Martin, Michelle Willicombe, Michelle Willicombe, Candice Roufosse, Candice Roufosse   +5 more
doaj   +1 more source

HLA-G: expression in human keratinocytes in vitro and in human skin in vivo [PDF]

, 1994
Classical, polymorphic major histocompatibility complex class I molecules are expressed on most nucleated cells.They present peptides at the cell surface and, thus, enable the immune system to scan peptides for their antigenicity.
Ulbrecht, M., Rehberger, B., Strobel, I., Messer, Gerald, Kind, P., Degitz, K., Bieber, T., Weiss, Elisabeth H.   +7 more
core   +2 more sources

Allele Frequency Analysis of HLA-A, -B, -DRB1, -DQA1, and -DQB1 Using LABTypeTM SSO in a Patient Cohort from Jeonbuk National University Hospital

Korean Journal of Clinical Laboratory Science
This retrospective, single-center study analyzed the distribution and frequency of HLA alleles in 238 patients who visited or were admitted to Jeonbuk National University Hospital between January 2023 and March 2024 and underwent HLA genotyping.
Ji Young MUN, Joonhong PARK
doaj   +1 more source

Preparation, Synergism, and Biocompatibility of in situ Liquid Crystals Loaded with Sinomenine and 5-Fluorouracil for Treatment of Liver Cancer

International Journal of Nanomedicine, 2021
Jiaojiao Cao,1,* Jie Huang,1,* Shuangying Gui,1,2 Xiaoqin Chu1,2 1Department of Pharmaceutics, Anhui University of Chinese Medicine, Hefei, 230012, People’s Republic of China; 2Institute of Pharmaceutics, Anhui Academy of Chinese Medicine, Hefei ...
Cao J, Huang J, Gui S, Chu X
doaj  

Drug Induced Hypersensitivity and the HLA Complex

Pharmaceuticals, 2010
Drug-induced hypersensitivity reactions are of major concern and present a burden for national healthcare systems due to their often severe nature, high rate of hospital admissions and high mortality. They manifest with a wide range of symptoms and signs,
Munir Pirmohamed, Ana Alfirevic
doaj   +1 more source

Comparison of methods for in-house screening of HLA*B57:01 to prevent abacavir hypersensitivity in HIV-1 care [PDF]

, 2015
Abacavir is a nucleoside reverse transcriptase inhibitor used as part of combination antiretroviral therapy in HIV-1-infected patients. Because this drug can cause a hypersensitivity reaction that is correlated with the presence of the HLA-B*57:01 ...
Bonczkowski, Pawel, Callens, Steven, Coucke, Paul, De Spiegelaere, Ward, De Wit, Stephane, Emonds, Marie-Paule, Kabeya, Kabamba, Kiselinova, Maja, Malatinková, Eva, Philippé, Jan, Ruelle, Jean, SERMIJN, ERICA, Trypsteen, Wim, Van Acker, Petra, Van Sandt, Vicky, Vandekerckhove, Linos, Verhofstede, Chris, VERVISCH, KAREN, Vogelaers, Dirk   +18 more
core   +4 more sources

A walk through the development of human leukocyte antigen typing: from serologic techniques to next-generation sequencing

Clinical Transplantation and Research
Human leukocyte antigen (HLA) is a group of glycoproteins encoded by the major histocompatibility complex (MHC) that plays a pivotal role in the host's immune defense.
Haeyoun Choi, Eun-Jeong Choi, Hyoung-Jae Kim, In-Cheol Baek, Aegyeong Won, Su Jin Park, Tai-Gyu Kim, Yeun-Jun Chung   +7 more
doaj   +1 more source

The Major Histocompatibility Complex in Transplantation

Journal of Transplantation, 2012
The transplant of organs is one of the greatest therapeutic achievements of the twentieth century. In organ transplantation, the adaptive immunity is considered the main response exerted to the transplanted tissue, since the principal target of the ...
Marco Antonio Ayala García, Beatriz González Yebra, Andrea Liliana López Flores, Eduardo Guaní Guerra   +3 more
doaj   +1 more source

Imputing amino acid polymorphisms in human leukocyte antigens.

PLoS ONE, 2013
DNA sequence variation within human leukocyte antigen (HLA) genes mediate susceptibility to a wide range of human diseases. The complex genetic structure of the major histocompatibility complex (MHC) makes it difficult, however, to collect genotyping ...
Xiaoming Jia, Buhm Han, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J Concannon, Stephen S Rich, Soumya Raychaudhuri, Paul I W de Bakker   +7 more
doaj   +1 more source