Results 101 to 110 of about 1,714,596 (353)

Renal outcomes of STOP-IgAN trial patients in relation to baseline histology (MEST-C scores) [PDF]

, 2018
Judith Schimpf, Till Klein, Christina Fitzner, Frank Eitner, Štefan Porubský, R.-D Hilgers, Jürgen Floege, Hermann-Josef Groene, Thomas Rauen   +8 more
openalex   +1 more source

Ex vivo comparison of ultrasonographic intestinal wall layering with histology in horses: A feasibility study [PDF]

, 2021

openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Biochemical and Histological Effects of Thiamine Pyrophosphate against Acetaminophen‐Induced Hepatotoxicity [PDF]

, 2015
Hilal Bektaş Uysal, Bekir Dağlı, M. Yılmaz, Fadime Kahyaoğlu, Alparslan Gökçimen, İmran Kurt Ömürlü, Buket Demirci   +6 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

BACH: Grand challenge on breast cancer histology images [PDF]

Medical Image Anal., 2018
Guilherme Aresta, Teresa Araújo, S. Kwok, Sai Saketh Chennamsetty, P. MohammedSafwanK., Alex Varghese, B. Marami, M. Prastawa, Monica Chan, M. Donovan, G. Fernandez, J. Zeineh, Matthias Kohl, C. Walz, Florian Ludwig, S. Braunewell, Maximilian Baust, Q. Vu, Minh Nguyen Nhat To, Eal Kim, J. T. Kwak, Sameh Galal, Veronica Sanchez-Freire, N. Brancati, Maria Frucci, D. Riccio, Yaqi Wang, Lingling Sun, Kaiqiang Ma, Jiannan Fang, Ismaël Koné, L. Boulmane, A. Campilho, C. Eloy, A. Polónia, Paulo Aguiar   +35 more
semanticscholar   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Line‐field confocal optical coherence tomography and optical coherence tomography for distinguishing basal cell carcinoma from dermal nevus: A case report

JEADV Clinical Practice
Basal cell carcinoma (BCC) is the most frequent skin cancer with a rising incidence. It can imitate benign lesions for example, dermal nevus clinically and dermoscopically.
Deborah Winkler, Anna Desch, Martha Paola Mireles, Julia Welzel, Sandra Schuh   +4 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source