Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer
Cells, 2019 Histone ubiquitination is a critical epigenetic mechanism regulating DNA-driven processes such as gene transcription and DNA damage repair. Importantly, the cellular machinery regulating histone ubiquitination is frequently altered in cancers.
Lucile M-P Jeusset, Kirk J McManus
doaj +1 more source
The DNA Single-Strand Break Repair Machinery Facilitates CAF-1-Mediated Histone Deposition at Oxidative DNA Strand Breaks [PDF]
arXiv, 2009 Oxidative DNA single strand breaks arise continuously in cells and defects in their repair have been implicated in neurological disease. While much progress has been made in understanding how chromosomal single strand breaks are repaired little is known about the changes chromatin structure that accompany this process.
arxiv
DeepDiff: Deep-learning for predicting Differential gene expression from histone modifications [PDF]
arXiv, 2018 Computational methods that predict differential gene expression from histone modification signals are highly desirable for understanding how histone modifications control the functional heterogeneity of cells through influencing differential gene regulation.
arxiv
A NEW MODIFIED PROTAMINE ZINC INSULIN: COMPARISON WITH HISTONE ZINC INSULIN, CLEAR, AND STANDARD PROTAMINE ZINC INSULINS 12 [PDF]
, 1943 CYRIL M. MacBRYDE, Harold K. Roberts
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Analysis of interaction partners of H4 histone by a new proteomics approach [PDF]
arXiv, 2009 We describe a modification of the TAP method for purification and analysis of multiprotein complexes, termed here DEF-TAP (for Differential Elution Fractionation after Tandem Affinity Purification). Its essential new feature is the use for last purification step of 6XHis-Ni++ interaction, which is resistant to a variety of harsh washing conditions ...
arxiv
Effect of heating and cooling on interaction of lysine-rich histones with deoxyribonucleic acid [PDF]
, 1969 Dragoš Cvetković, Radoslav Savić
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EVIDENCE For THE CYTOPLASMIC SYNTHESIS OF NUCLEAR HISTONE DURING SPERMIOGENESIS IN THE GRASSHOPPER CHORTOPHAGA VIRIDIFASCIATA (DE GEER) [PDF]
, 1964 David P. Bloch, Sheilah D. Brack
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THE SYNTHESES OF DEOXYRIBONUCLEIC ACID AND HISTONE IN THE ONION ROOT MERISTEM [PDF]
, 1967 David P. Bloch +3 more
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Regulation of chromatin by histone modifications
Cell Research, 2011 Andrew J. Bannister, T. Kouzarides
semanticscholar +1 more source