Histone Lactylation in Diseases: Regulation by Traditional Chinese Medicine and Therapeutic Implications. [PDF]
Qiu Y, Shao X.
europepmc +1 more source
Relative Metabolic Activities of Histones in Tumours and Liver [PDF]
J. A. V. Butler, D. J. R. Laurence
openalex +1 more source
Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao+13 more
wiley +1 more source
Contribution of reversible histone acetylation to freeze tolerance and recovery in wood frog kidneys. [PDF]
Taiwo OO, Storey KB.
europepmc +1 more source
Effect of Histones and Protamine on the Infectivity of Semliki Forest Virus and its Ribonucleic Acid [PDF]
Joanne Connolly
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ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Advances in the Epigenetic Mechanisms of Diabetic Nephropathy Pathogenesis. [PDF]
Zhang C+12 more
europepmc +1 more source
piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang+16 more
wiley +1 more source
PFKM phosphorylates histone H3 and promotes mitotic progression by sensing the levels of citrate. [PDF]
Lin P+11 more
europepmc +1 more source