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Benchmarking peak calling methods for CUT&RUN. [PDF]
Nooranikhojasteh A+2 more
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Epi-nutrients for cancer prevention: Molecular mechanisms and emerging insights. [PDF]
Bakrim S+12 more
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Histone serotonylation promotes pancreatic cancer development via lipid metabolism remodeling. [PDF]
Lin S+13 more
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Statins and their impact on epigenetic regulation: insights into disease. [PDF]
Tamayo-Trujillo R+5 more
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Histone Acetylation and Histone Deacetylation
Molecular Biotechnology, 2002Regulation of inflammatory gene transcription is controlled, at least in part, by the degree of local unwinding of nucleosomal DNA. This unwinding is regulated by histone acetylation--increased acetylation results in a more loosely wound structure allowing access of basal transcription factors and RNA polymerase II.
Kazuhiro Ito, Ian M. Adcock
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Science, 1976
Highly specific antibodies were raised to histone 1 (H1) and the histone complexes H3 2 -H4 2 and H2A-H2B, isolated by salt extraction. Antibody to H1 could detect irreversible conformational changes in acid- or urea-treated H1. The antibodies showed different reactivities with chromosomes as
Orlando J. Miller+2 more
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Highly specific antibodies were raised to histone 1 (H1) and the histone complexes H3 2 -H4 2 and H2A-H2B, isolated by salt extraction. Antibody to H1 could detect irreversible conformational changes in acid- or urea-treated H1. The antibodies showed different reactivities with chromosomes as
Orlando J. Miller+2 more
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Yeast inner histones and the evolutionary conservation of histone-histone interactions
Biochemistry, 1978The inner histones of the yeast, Saccharomyces cerevisiae, have been isolated and identified by their amino acid compositions. H4 appears to be close to its calf and pea counterparts. H2a, H2b, and H3 have diverged. The isolation of the histones was accomplished by consecutive slab-gel fractionation, and a number of novel features of the method are ...
James K.W. Mardian, Irvin Isenberg
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Histone Variants and Histone Modifications in Neurogenesis
Trends in Cell Biology, 2020During embryonic brain development, neurogenesis requires the orchestration of gene expression to regulate neural stem cell (NSC) fate specification. Epigenetic regulation with specific emphasis on the modes of histone variants and histone post-translational modifications are involved in interactive gene regulation of central nervous system (CNS ...
Mengtian Zhang+8 more
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