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Mammalian histone acetyltransferases and their complexes

Cellular and Molecular Life Sciences, 2001
One of the key questions in the current molecular genetics of eukaryotes is how genetic information is retrieved from tightly packed chromatin. Acetylation of core histone N-termini is implicated in the regulation of chromatin function, and I summarize what is known about the mammalian enzymes that promote this posttranslational histone modification ...
openaire   +2 more sources

Measurement of histone acetyltransferase and histone deacetylase activities and kinetics of histone acetylation

Methods, 2003
Dynamic histone acetylation has a role in chromatin remodeling and in the regulation of transcription. Histone deacetylases (HDACs) and histone acetyltransferases (HATs) catalyze reversible histone acetylation. HATs and HDACs exist as multiprotein complexes that have coactivator and corepressor activities, respectively.
Jian-Min, Sun   +4 more
openaire   +2 more sources

Histone acetyltransferases and histone deacetylases of Physarum polycephalum

Cell Biology International Reports, 1992
Abstract DEAE-Sepharose chromatography of plasmodial extracts of the myxomycete Physarum polycephalum reveals the presence of multiple histone acetyltransferases and histone deacetylases. Five putative histone acetyltransferases and histone deacetylases.
G BROSCH   +5 more
openaire   +1 more source

Regulation of plant architecture by a new histone acetyltransferase targeting gene bodies

Nature Plants, 2020
Xueyong Yang   +11 more
semanticscholar   +1 more source

Histone acetyltransferases in control.

Current biology : CB, 1997
Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.
P A, Wade, A P, Wolffe
openaire   +1 more source

Histone Acetyltransferases

2015
Yepeng Luan   +5 more
openaire   +2 more sources

Recent insights into Histone Acetyltransferase-1: biological function and involvement in pathogenesis

Epigenetics, 2021
Angela Nebbioso   +2 more
exaly  

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