Results 231 to 240 of about 237,704 (293)

Differential transcriptomic modulation by histone deacetylase inhibitor SAHA in LUAD and LUSC. [PDF]

Clin Epigenetics
Wang F, Yang Q, Shu L, Cen H, Huang Y, Ma X, Lin Y, Guan X, Wang C, Fu X, You G, Yu XY, Zhang L, Su J.   +13 more
europepmc   +1 more source

Astragaloside IV Restores Autophagy and Inhibits Apoptosis for Podocyte Protection in Diabetic Nephropathy by Inhibiting Notch1 Signaling via SIRT6‐Mediated Deacetylation

Phytotherapy Research, EarlyView.
AS‐IV binds to SIRT6 and promotes H3K9 deacetylation at the Notch1 promoter, inhibiting gene transcription (Created with BioGDP.com). ABSTRACT Astragaloside IV (AS‐IV) has demonstrated efficacy in ameliorating proteinuria and attenuating renal tubular damage in preclinical diabetic nephropathy (DN) models.
Qiyu Yue, Chen Yong, Xinran Wang, Yang Shu, Min Yao, Yongfei Yu, Yubai Xue, Rong Deng, Tianlu Chu, Weiwei Tao, Min Zhao, Enchao Zhou   +11 more
wiley   +1 more source

Histone deacetylase activity limits the response to EZH2 inhibition-based therapy in epithelioid sarcoma and is targetable by epigenetic combination

Arrighetti N, Soffientini C, Zuco V, Percio S, Cleris L, Ahmed SA, Savio ED, Sigalotti L, Maestro R, Brich S, Dagrada GP, Barisella M, Collini P, Kentsis A, Huang PH, Gronchi A, Frezza AM, Stacchiotti S, Zaffaroni N, Pasquali S.   +19 more
europepmc   +1 more source

Adverse drug reaction profiles of histone deacetylase inhibitors. [PDF]

Sci Rep
Begum R, Parsons JL, Jones AM.
europepmc   +1 more source

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source

Characterization of histone acetyltransferase and histone deacetylase genes under abiotic and hormone stresses in soybean. [PDF]

Front Plant Sci
Liu K, Sun S, Guo E, Liu X, Duan M, Zhang H, Xue C, Wei Z, Gong Z.   +8 more
europepmc   +1 more source

Multiscale Effects of Environmentally Relevant Mixtures Containing Two Estrogenic Endocrine Disruptors, Chlordecone and Propylparaben, in Hydra vulgaris Pallas, 1766

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates the chronic effects of chlordecone (CLD) and propylparaben (PP), two pro‐estrogenic endocrine disruptors, on Hydra vulgaris Pallas, 1766 using a multiscale approach over a 14‐day exposure period. Environmentally relevant concentrations of CLD (0.5, 5, 20 μg L−1) and PP (0.01, 0.05, 0.40 μg L−1) were tested individually ...
Magali Domallain, Romain Colpaert, Xavier Moreau, Laetitia De Jong, Karim Benbrahim, Raphael Coatmeur, Valérie Pique, Maxime Robin, Pierre‐Henri Villard   +8 more
wiley   +1 more source

Imaging brain class I histone deacetylase changes in the Lewy body dementias and Parkinson's disease. [PDF]

Clin Epigenetics
Goodheart AE, Yoo CH, Fassini A, Dagnew TM, Ye R, Striar R, Quan M, Rattray AK, Meyer TN, Peterec E, Lee H, Fiedler SA, Hooker JM, Wey HY, Wang C, Gomperts SN.   +15 more
europepmc   +1 more source

Anti-tumor effect of a histone deacetylase inhibitor on canine malignant melanoma. [PDF]

J Vet Med Sci
Li T, Shibahara H, Kato D, Kodera Y, Ikeda N, Shinada M, Iguchi T, Shiyu Q, Ando M, Koseki S, Kako T, Motoi H, Hashimoto Y, Takahashi Y, Nishimura R, Nakagawa T.   +15 more
europepmc   +1 more source

Microglial histone deacetylase-3 conditional deletion attenuates neurological deficits after intracerebral hemorrhage. [PDF]

Front Cell Neurosci
Watson NJ, Xu H, Sukumari-Ramesh S.
europepmc   +1 more source