Results 251 to 260 of about 182,853 (310)

Histone deacetylase inhibitors sensitize glioblastoma models to temozolomide and reprogram immunosuppressive myeloid cells. [PDF]

Sci Rep
Tehrani GA, Kubick RN, Zarodniuk M, Datta M.   +3 more
europepmc   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

The SNL Histone Deacetylase-Binding Factor GmHE13 Is a Novel Regulator of Soybean Hypocotyl Elongation. [PDF]

Plant Biotechnol J
Shen Z, Zhuang L, Zhang W, Liang F, Peng Y, Yuan M, Zhang W, Zhang P, Li X, Wang W, Chen M.   +10 more
europepmc   +1 more source

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, EarlyView.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source

Design, synthesis and antiproliferative activity of oxadiazole derivatives as potent glycogen synthase kinase-3/histone deacetylase 6 dual inhibitors. [PDF]

J Enzyme Inhib Med Chem
Ye C, Chen Z, Jiang J, Li J, Kong R, Liu S, Chen X, Xu Z.   +7 more
europepmc   +1 more source

Exploiting ALK inhibition in anaplastic large cell lymphoma: Biological rationale and therapeutic integration

British Journal of Haematology, EarlyView.
Summary Mature T‐cell lymphomas comprise a heterogeneous group of aggressive non‐Hodgkin lymphomas with limited therapeutic options in the relapsed or refractory setting. Among them, anaplastic lymphoma kinase (ALK)‐positive anaplastic large cell lymphoma (ALCL) represents a biologically distinct subtype driven by constitutive activation of ALK fusion ...
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +13 more
wiley   +1 more source

Histone deacetylase HDA-5 regulates lipid metabolism through H4K5 and H4K8 acetylation in Caenorhabditis elegans. [PDF]

J Biol Chem
Wu QY, Zhou M, Zhu R, Gu KZ, Ma YC, Zou CG.   +5 more
europepmc   +1 more source

Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review). [PDF]

Int J Mol Med
Wang J, Zhao Q, Zhang S, Liu J, Fan X, Han B, Hou Y, Ai X.   +7 more
europepmc   +1 more source

Inhibition of histone deacetylase 3 in dental mesenchyme regulates the development of tooth root. [PDF]

J Bone Miner Res
Niibe K, Begun DL, Doi-Fujimura K, Nagasaki A, Zars E, Li X, Taylor EL, MacDougall MB, Egusa H, Westendorf JJ.   +9 more
europepmc   +1 more source