Results 261 to 270 of about 182,853 (310)

Novel selective indole based histone deacetylase 10 inhibitors as anticancer therapeutics. [PDF]

Sci Rep
Tarawneh AH, Al-Trawneh SA, Yesiloglu TZ, Zessin M, Robaa D, Barinka C, Schutkowski M, Sippl W, Ross SA.   +8 more
europepmc   +1 more source

Histone deacetylase SIRT6 regulates tryptophan catabolism and prevents metabolite imbalance associated with neurodegeneration. [PDF]

Nat Commun
Kaluski-Kopatch S, Stein D, Venzor AG, Ferreira Campos AM, Planque M, Goldstein B, De Allende-Becerra E, Smirnov D, Zaretsky A, Eremenko E, Portillo M, Einav M, Krejci AB, Abdu U, Khrameeva E, Gitler D, Fendt SM, Toiber D.   +17 more
europepmc   +1 more source

Histone deacetylase 6 inhibits STING-dependent antiviral immunity via site-specific deacetylation. [PDF]

J Biol Chem
Qu M, Wei D, Ke Q, Cheng P, Ma Y, Afera B, Guo K, Li M, Yin X, Wang X, Han J, Sun Y.   +11 more
europepmc   +1 more source

Histone deacetylase HDAC7 restricts CD8 + T cell tumor infiltration and limits immunotherapy sensitivity in bladder cancer: reversal by pinocembrin. [PDF]

J Exp Clin Cancer Res
Lv J, Li K, Zhou J, Yu R, Lu Q, Liu B.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Histone deacetylases

Current Opinion in Pharmacology, 2003
Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events include histone deacetylases (class I and class II), which can be inhibited by a structurally diverse group of small molecules.
Paul A, Marks, Thomas, Miller, Victoria M, Richon   +2 more
openaire   +2 more sources

Histone Deacetylase Inhibitors

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller, David J, Witter, Sandro, Belvedere   +2 more
openaire   +2 more sources

Histone Deacetylases

2008
Deacetylation of histones is required for gene regulation and cell cycle progression and the mediators, the histone deacetylases, are being vigorously pursued as drug targets for cancer chemotherapy. The deacetylases are also potential drug targets against infectious diseases and genome sequencing revealed proteins of this class in each of three ...
  +6 more sources

Histone Deacetylase Inhibitors

2004
The base sequence of DNA provides the genetic code for proteins. The regulation of expression or suppression of gene transcription is largely determined by the structure of the chromatin--referred to as epigenetic gene regulation (Agalioti et al., 2002; Jenuwein and Allis, 2001; Richards and Elgin, 2002; Spotswood and Turner, 2002; Zhang and Reinberg ...
Paul A, Marks, Victoria M, Richon, Thomas, Miller, William Kevin, Kelly   +3 more
openaire   +2 more sources

Histone deacetylase inhibitors

European Journal of Medicinal Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Histone deacetylase in neuropathology

2021
Neuroepigenetics, a new branch of epigenetics, plays an important role in the regulation of gene expression. Neuroepigenetics is associated with holistic neuronal function and helps in formation and maintenance of memory and learning processes. This includes neurodevelopment and neurodegenerative defects in which histone modification enzymes appear to ...
Rohan, Gupta, Rashmi K, Ambasta, Pravir, Kumar   +2 more
openaire   +2 more sources