Results 161 to 170 of about 18,392,427 (194)

Histone deacetylase 3 controls a transcriptional network required for B cell maturation. [PDF]

open access: yesNucleic Acids Res, 2019
Stengel KR   +6 more
europepmc   +1 more source

The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3. [PDF]

open access: yesScience, 2019
Kuang Z   +7 more
europepmc   +1 more source
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The role of histone deacetylase 3 in breast cancer

Medical Oncology, 2022
It has been recently revealed that Histone Deacetylase (HDAC) 3, a unique member of the HDACs family, can trigger and progress cancers by alternation in genes expression and proteins activity. Epigenetic modifications by HDACs have been studied well in various cancer cells.
Rezgar Rahbari   +3 more
openaire   +2 more sources

Therapeutic potential of selective histone deacetylase 3 inhibition

European Journal of Medicinal Chemistry, 2019
Histone deacetylases (HDACs) are closely related to the occurrence and development of a variety of diseases, such as tumor, inflammation, diabetes mellitus, cardiovascular and neurodegenerative diseases. Inhibition of HDACs by developing HDAC inhibitors has achieved significant progress in the treatment of diseases caused by epigenetic abnormalities ...
Lihui, Zhang   +4 more
openaire   +2 more sources

Histone deacetylase 3 inhibitor attenuates diabetic retinopathy in mice

Journal of Neurophysiology, 2023
The study demonstrated that RGFP966 significantly reduced oxidative stress, inflammation, and cell apoptosis in the retina of streptozotocin-induced diabetic mice, which may be associated with Nox2 and Sod2 expression.
Yu Jiang, Bo Luo
openaire   +2 more sources

Integrative function of histone deacetylase 3 in inflammation

Molecular Biology Reports
Inflammation is a complex biological response triggered when an organism encounters internal or external stimuli. These triggers activate various signaling pathways, leading to the release of numerous inflammatory mediators aimed at the affected tissue.
Junjie Li, Yiyuan Zhai, Min Tang
openaire   +2 more sources

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