Results 271 to 274 of about 155,197 (274)

N-(2-Amino-phenyl)-4-(heteroarylmethyl)-benzamides as new histone deacetylase inhibitors

Bioorganic & Medicinal Chemistry Letters, 2007
A variety of N-(2-amino-phenyl)-4-(heteroarylmethyl)-benzamides were designed and synthesized. These compounds were shown to inhibit recombinant human HDAC1 with IC(50) values in the sub-micromolar range. In human cancer cells growing in culture these compounds induced hyperacetylation of histones, induced the expression of the tumor suppressor protein
Arkadii, Vaisburg, Isabelle, Paquin, Naomy, Bernstein, Sylvie, Frechette, Frederic, Gaudette, Silvana, Leit, Oscar, Moradei, Stephane, Raeppel, Nancy, Zhou, Giliane, Bouchain, Soon Hyung, Woo, Zhiyun, Jin, Jeff, Gillespie, James, Wang, Marielle, Fournel, Pu Theresa, Yan, Marie-Claude, Trachy-Bourget, Marie-France, Robert, Aihua, Lu, Jimmy, Yuk, Jubrail, Rahil, A Robert, Macleod, Jeffrey M, Besterman, Zuomei, Li, Daniel, Delorme   +24 more
openaire   +2 more sources

Histone Deacetylase 4 is crucial for proper skeletal muscle development and disease

2015
Italian Journal of Anatomy and Embryology, Vol. 120, No.
MARRONCELLI, NICOLETTA, PIGNA, EVA, C. Noviello, S. Di Francescantonio, E. Greco, COLETTI, Dario, ADAMO, Sergio, MORESI, Viviana   +7 more
openaire   +1 more source

Histone deacetylase (HDAC) 4 involvement in both Lewy and Marinesco bodies

Neuropathology and Applied Neurobiology, 2006
J, Takahashi-Fujigasaki, H, Fujigasaki
openaire   +2 more sources

4-Hexylresorcinol as Histone Deacetylase Inhibitor

openaire   +1 more source