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Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents
Current Medicinal Chemistry, 2020Histone deacetylase (HDAC) inhibitors are a relatively new class of anti-cancer agents that play important roles in epigenetic or non-epigenetic regulation, inducing death, apoptosis, and cell cycle arrest in cancer cells.
Loredana Cappellacci +2 more
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Anticancer activities of histone deacetylase inhibitors
Nature Reviews Drug Discovery, 2006Ricky Johnstone, Johnstone Ricky W
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Recent histone deacetylase inhibitors in cancer therapy
Cancer, 2023Cancer metastasis increases the complexity of the disease and escalates patient mortality. Traditional chemotherapy has been associated with low efficacy and marked side effects.
Roza Parveen +2 more
semanticscholar +1 more source
Strategies To Design Selective Histone Deacetylase Inhibitors
ChemMedChem, 2021This review classifies drug‐design strategies successfully implemented in the development of histone deacetylase (HDAC) inhibitors, which have many applications including cancer treatment. Our focus is on especially demanded selective HDAC inhibitors and
Jelena Melesina +5 more
semanticscholar +1 more source
Inhibitors of histone deacetylase as antitumor agents: A critical review
Bioorganic Chemistry, 2016M J Nanjan, M J N Chandrasekar
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Histone deacetylase inhibitors
European Journal of Medicinal Chemistry, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
BRESSI JEROME C +2 more
openaire +6 more sources
Histone Deacetylase Inhibitors
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller +2 more
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Histone deacetylase 3 (HDAC3) inhibitors as anticancer agents: A review.
European journal of medicinal chemistry, 2020Among different Histone deacetylases (HDACs), histone deacetylase 3 (HDAC3) is an epigenetic drug target which is currently marked as a potential therapeutic strategy to combat various cancers. HDAC3 inhibitors are effective for the treatment of cancers,
Rajat Sarkar +4 more
semanticscholar +1 more source

