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Histone Deacetylase Inhibitors Show a Potential Leishmanicidal Effect against Leishmania braziliensis in a Mouse Infection Model and Lead to Less Toxicity than Glucantime. [PDF]

open access: yesACS Omega
de Souza LÂ   +21 more
europepmc   +1 more source
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Histone deacetylase inhibitors

European Journal of Medicinal Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
BRESSI JEROME C   +2 more
openaire   +6 more sources

Histone Deacetylase Inhibitors

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller   +2 more
openaire   +2 more sources

Histone Deacetylase Inhibitors in Tumor Immunotherapy

open access: yesCurrent Medicinal Chemistry, 2019
Background:With an increasing understanding of the antitumor immune response, considerable progress has been made in the field of tumor immunotherapy in the last decade.
Li-Ming Zhao
exaly   +2 more sources

HISTONE DEACETYLASE INHIBITORS

2004
The base sequence of DNA provides the genetic code for proteins. The regulation of expression or suppression of gene transcription is largely determined by the structure of the chromatin--referred to as epigenetic gene regulation (Agalioti et al., 2002; Jenuwein and Allis, 2001; Richards and Elgin, 2002; Spotswood and Turner, 2002; Zhang and Reinberg ...
JOEL SIMON, MARSON CHARLES, SAVY PASCAL
openaire   +6 more sources

Carbamazepine is an inhibitor of histone deacetylases

Life Sciences, 2005
Carbamazepine (CBZ) is a common antiepileptic drug (AED) that acts through multiple mechanisms including blockade and potentiation of cation channels and modulation of neurotransmitter levels. Whether it affects any component of the gene transcription machinery is unknown.
Andreas S, Beutler   +3 more
openaire   +2 more sources

Prospects: Histone deacetylase inhibitors

Journal of Cellular Biochemistry, 2005
AbstractHistone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients.
Milos, Dokmanovic, Paul A, Marks
openaire   +2 more sources

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