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Histone Deacetylase Inhibitors Show a Potential Leishmanicidal Effect against Leishmania braziliensis in a Mouse Infection Model and Lead to Less Toxicity than Glucantime. [PDF]
de Souza LÂ +21 more
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Epi-revolution in rheumatology: the potential of histone deacetylase inhibitors for targeted rheumatoid arthritis intervention. [PDF]
Pai P +4 more
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Charting a path through resistance: histone deacetylase inhibitors for TP53-mutated B-cell acute lymphoblastic leukemia. [PDF]
Kugler E.
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Histone deacetylase inhibitors
European Journal of Medicinal Chemistry, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
BRESSI JEROME C +2 more
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Histone Deacetylase Inhibitors
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller +2 more
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Histone Deacetylase Inhibitors in Tumor Immunotherapy
Background:With an increasing understanding of the antitumor immune response, considerable progress has been made in the field of tumor immunotherapy in the last decade.
Li-Ming Zhao
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HISTONE DEACETYLASE INHIBITORS
2004The base sequence of DNA provides the genetic code for proteins. The regulation of expression or suppression of gene transcription is largely determined by the structure of the chromatin--referred to as epigenetic gene regulation (Agalioti et al., 2002; Jenuwein and Allis, 2001; Richards and Elgin, 2002; Spotswood and Turner, 2002; Zhang and Reinberg ...
JOEL SIMON, MARSON CHARLES, SAVY PASCAL
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Carbamazepine is an inhibitor of histone deacetylases
Life Sciences, 2005Carbamazepine (CBZ) is a common antiepileptic drug (AED) that acts through multiple mechanisms including blockade and potentiation of cation channels and modulation of neurotransmitter levels. Whether it affects any component of the gene transcription machinery is unknown.
Andreas S, Beutler +3 more
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Prospects: Histone deacetylase inhibitors
Journal of Cellular Biochemistry, 2005AbstractHistone deacetylase (HDAC), inhibitors represent a new class of targeted anti‐cancer agents. Several of these compounds are in clinical trials with significant activity against a spectrum of both hematologic and solid tumors at doses that are well tolerated by the patients.
Milos, Dokmanovic, Paul A, Marks
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