Results 251 to 260 of about 113,596 (299)

TORSEL, a 4EBP1-based mTORC1 live-cell sensor, reveals nutrient-sensing targeting by histone deacetylase inhibitors. [PDF]

Cell Biosci
Li C, Yi Y, Ouyang Y, Chen F, Lu C, Peng S, Wang Y, Chen X, Yan X, Xu H, Li S, Feng L, Xie X.   +12 more
europepmc   +1 more source

Synthesis of inhibitors of histone deacetylase

, 2009
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Sulfur(VI) Fluoride Exchange Chemistry in Solid-Phase Synthesis of Compound Arrays: Discovery of Histone Deacetylase Inhibitors. [PDF]

JACS Au
Hansen TN, Danková D, Bæk M, Grlaš L, Olsen CA.   +4 more
europepmc   +1 more source

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Histone Deacetylase Inhibitors

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller, David J, Witter, Sandro, Belvedere   +2 more
openaire   +2 more sources

Carbamazepine is an inhibitor of histone deacetylases

Life Sciences, 2005
Carbamazepine (CBZ) is a common antiepileptic drug (AED) that acts through multiple mechanisms including blockade and potentiation of cation channels and modulation of neurotransmitter levels. Whether it affects any component of the gene transcription machinery is unknown.
Andreas S, Beutler, SiDe, Li, Rebekka, Nicol, Martin J, Walsh   +3 more
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Selective Histone Deacetylase Inhibitors

Anti-Cancer Agents in Medicinal Chemistry, 2012
Histone deacetylases (HDACs) are a family of conserved metalloproteases which play a key role in the development of cancer. They can be divided into 18 subtypes according to their structural diversity. Histone deacetylase inhibitors are considered as potential anti-cancer agents and a lot of pan-HDAC inhibitors have entered clinical trials.
Huili, Pan, Jiangying, Cao, Wenfang, Xu
openaire   +2 more sources

Histone deacetylase inhibitors

European Journal of Medicinal Chemistry, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Histone Deacetylase Inhibitors

2004
The base sequence of DNA provides the genetic code for proteins. The regulation of expression or suppression of gene transcription is largely determined by the structure of the chromatin--referred to as epigenetic gene regulation (Agalioti et al., 2002; Jenuwein and Allis, 2001; Richards and Elgin, 2002; Spotswood and Turner, 2002; Zhang and Reinberg ...
Paul A, Marks, Victoria M, Richon, Thomas, Miller, William Kevin, Kelly   +3 more
openaire   +2 more sources