Results 161 to 170 of about 98,157 (333)

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Plant responses to abiotic stress regulated by histone acetylation

open access: yesFrontiers in Plant Science
In eukaryotes, histone acetylation and deacetylation play an important role in the regulation of gene expression. Histone acetylation levels are reversibly regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs).
Fei Wang   +10 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

How Histone Deacetylases Control Myelination [PDF]

open access: yes, 2018
Myelinated axons are a beautiful example of symbiotic interactions between two cell types: Myelinating glial cells organize axonal membranes and build their myelin sheaths to allow fast action potential conduction, while axons regulate myelination and ...
Jacob, Claire   +2 more
core  

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Supplementary Figures 1-6 from Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels

open access: gold, 2023
Leo Kretzner   +9 more
openalex   +2 more sources

Automated analysis of postictal generalized electroencephalogram suppression for SUDEP risk stratification

open access: yesEpilepsia Open, EarlyView.
Abstract Sudden unexpected death in epilepsy (SUDEP) affects more than 3000 individuals annually, yet objective and scalable biomarkers to assess risk remain limited. Postictal generalized electroencephalogram suppression (PGES) has been proposed as a potential biomarker, but its quantification is often subjective and variable.
Steve D. Reddy   +3 more
wiley   +1 more source

Epigenome Modifying Tools In Asthma [PDF]

open access: yes, 2015
Adcock,, Brook, PO, Durham, AL, Perry, M
core   +1 more source

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