Results 171 to 180 of about 53,170 (215)

2‐Amino‐3H‐phenoxazin‐3‐one is a lead inhibitor of Cuscuta campestris early development: structure–activity relationships of o‐aminophenol‐derived allelochemicals

Pest Management Science, EarlyView.
Phenoxazinones caused differential types of phytotoxic effects in C. campestris early development. APO is a coherent lead inhibiting C. campestris germination and early seedling growth. Abstract BACKGROUND 2‐Amino‐3H‐phenoxazin‐3‐one (synonym: questiomycin A; abbreviated as APO or Phx‐3) is a naturally occurring phenoxazinone‐type allelochemical with ...
Cristina Díaz‐Franco, Mónica Fernández‐Aparicio, José MG Molinillo, Rosa M Varela, Francisco A Macías, Jesús G Zorrilla   +5 more
wiley   +1 more source

Integrative Analysis of Histone Deacetylases Reveals the Potential Role and Prognostic Value of HDAC7 in Hepatocellular Carcinoma. [PDF]

J Cancer
Yang C, Yu Z, Wang R, Zhang M, Zhao Z.
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Targeted Degradation of Histone Deacetylases via Bypassing E3 Ligase Targeting Chimeras (BYETACs). [PDF]

ACS Med Chem Lett
Sun T, Zhai S, König B, Honin I, Kponomaizoun CE, Hansen FK.   +5 more
europepmc   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

The Role of the Sirtuin Family Histone Deacetylases in Acute Myeloid Leukemia-A Promising Road Ahead. [PDF]

Cancers (Basel)
Strzałka P, Krawiec K, Wiśnik A, Jarych D, Czemerska M, Zawlik I, Pluta A, Wierzbowska A.   +7 more
europepmc   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Mapping the Interactions Among Class IIa Histone Deacetylases and Myocyte Enhancer Factor 2s. [PDF]

J Chem Inf Model
Gautam N, Wang S, Üren A, Chapagain PP, Adhikari NP, Tiwari PB.   +5 more
europepmc   +1 more source

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

Histone deacetylases: the critical enzymes for microglial activation involved in neuropathic pain. [PDF]

Front Pharmacol
Ding Y.
europepmc   +1 more source