Results 191 to 200 of about 360,616 (327)

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context‐Dependent Manner

Immunity, 2018
Moumita Datta, O. Staszewski, E. Raschi, Maximilian Frosch, N. Hagemeyer, T. Tay, T. Blank, M. Kreutzfeldt, D. Merkler, Stephanie Ziegler-Waldkirch, P. Matthias, Melanie Meyer‐Luehmann, M. Prinz   +12 more
semanticscholar   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

Epileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini, Evripidis Pityrigkas, Zoi Kallia, Georgia Pepe, Antonis Frontistis, Dimitrios Profer, Vasilios Kimiskidis   +6 more
wiley   +1 more source

Functional divergence and structural changes of Class IV histone deacetylases (HDACs) across the tree of life. [PDF]

Mol Biol Evol
Nováková Z, Bartošová-Sojková P, Kudláčová J, Baselious F, Kutilová Z, Jaklová P, Meleshin M, Motlová L, Schenkmayerova A, Vrkoslav V, Strnad Š, Horáček N, Gruber A, Žáček P, Kroll S, Havlínová B, Ondráková M, Tučková R, Krunclová T, Cvačka J, Oborník M, Schutkowski M, Sippl W, Bařinka C.   +23 more
europepmc   +1 more source

Insights into ANKRD11‐related epilepsy from 163 people

Epilepsia, EarlyView.
Abstract Objective Ankyrin repeat domain 11 gene (ANKRD11) is the key disease gene for autosomal dominant KBG syndrome, and a subset of affected individuals develop epilepsy. However, comprehensive characterization of epilepsy‐related phenotypes and genotype–phenotype correlations in ANKRD11 variant carriers remains limited.
Song Su, Jian Ma, Qi Zhang, Wandong Hu, Ying Ren, Wenchao Zhang, Hongwei Zhang   +6 more
wiley   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Discovery of a CI-994 derivative as a dual modulator of class I histone deacetylases and Wnt/β-catenin signaling for Alzheimer's disease therapy. [PDF]

Neurotherapeutics
Lu W, Caulfield TR, Lee E, Jeevaratnam S, Wang N, Bu G, Kanekiyo T, Li Y.   +7 more
europepmc   +1 more source

Epigenetic Dysregulation in Neurodegeneration: The Role of Histone Deacetylases and Emerging Inhibitor Strategies. [PDF]

Biomolecules
Pawar Y, Kopranovic A, C S R, Meyer-Almes FJ.   +3 more
europepmc   +1 more source

FSP1 and histone deacetylases suppress cancer persister cell ferroptosis. [PDF]

Sci Adv
Higuchi M, Williams AF, Stuhlfire AE, Nguyen AH, Gervasio DAG, Turkal CE, Chon S, Hangauer MJ.   +7 more
europepmc   +1 more source

Histone deacetylases and cell-cycle regulators orchestrate cell-identity transitions during Arabidopsis root regeneration. [PDF]

Mol Plant
Rahni R, Lee LR, Vissers G, Suresh I, Gorodokin BM, Ip PL, Guillotin B, Birnbaum KD.   +7 more
europepmc   +1 more source

Serotonin neuromicrobiology: Psychobiotic modulation of the gut–brain axis for mental health

Ibrain, EarlyView.
An overview of Psychobiotics and Tryptophan metabolism: A serotonin‐kynurenine crosstalk shaping the Gut‐Brain axis. IDO1, Indoleamine 2,3‐dioxygenase 1; 5‐HT3, 5‐hydroxytryptamine type 3; IFN‐γ, Interferon‐gamma; TNF‐α, Tumor necrosis factor‐alpha; IL‐1β, Interleukin‐1 beta; IL‐6, Interleukin 6; Trp, Tryptophan; 5‐HT, 5‐hydroxy‐tryptamine; 5‐HTP, 5 ...
Nidhi Mandloi, Aarzoo, Chakkaravarthi Saravanan, Heera Ram, Bhim Pratap Singh   +4 more
wiley   +1 more source