Results 301 to 310 of about 98,638 (334)
Investigating Potential Cancer Therapeutics: Insight into Histone Deacetylases (HDACs) Inhibitions. [PDF]
Ahmad B +8 more
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Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets. [PDF]
Lewis A +21 more
europepmc +1 more source
Synthesis and biological evaluation of ortho-phenyl phenylhydroxamic acids containing phenothiazine with improved selectivity for class IIa histone deacetylases. [PDF]
Hsu KC +8 more
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Dual targeting of histone deacetylases and MYC as potential treatment strategy for H3-K27M pediatric gliomas. [PDF]
Algranati D +10 more
europepmc +1 more source
Construction and verification of a histone deacetylases-related prognostic signature model for colon cancer. [PDF]
Hao L, Lu W, Wu J, Chen Y, Xu D, Wang P.
europepmc +1 more source
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Current Opinion in Pharmacology, 2003
Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events include histone deacetylases (class I and class II), which can be inhibited by a structurally diverse group of small molecules.
Paul A, Marks +2 more
openaire +2 more sources
Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events include histone deacetylases (class I and class II), which can be inhibited by a structurally diverse group of small molecules.
Paul A, Marks +2 more
openaire +2 more sources
Histone Deacetylase Inhibitors
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller +2 more
openaire +2 more sources

