Results 301 to 310 of about 98,157 (333)

A Multifunctional β‐Defensin‐3 Mimetic Peptide Modulates Host–Biofilm Interactions and Reduces Bone Loss in Periodontitis

Journal of Periodontal Research, EarlyView.
BDMP, a peptide that can penetrate cells and tissues, offering antimicrobial and anti‐inflammatory effects, has been identified as a potential new therapy for periodontitis. ABSTRACT Aim This study evaluated the potential of a beta‐defensin‐3 mimetic peptide (BDMP), a synthetic cell‐penetrating peptide with antimicrobial and immunomodulatory properties,
Beom Soo Jo, Dong Woo Lee, Ji‐Young Lee, Sanghui Seok, Yu‐Bin Kim, Jue‐Yeon Lee, Shin‐Young Park, Young Dan Cho, Yang Jo Seol, Yoon Shin Park, Shahram Ghanaati, Homayoun H. Zadeh, Chong Pyung Chung, Yoon Jeong Park   +13 more
wiley   +1 more source

Correction: Li et al. Histone Deacetylases as Epigenetic Targets for Treating Parkinson's Disease. <i>Brain Sci.</i> 2022, <i>12</i>, 672. [PDF]

Brain Sci
Li Y, Gu Z, Lin S, Chen L, Dzreyan V, Eid M, Demyanenko S, He B.   +7 more
europepmc   +1 more source

Gene expression of metabotropic glutamate receptors and histone deacetylases in postmortem prefrontal cortex of subjects with bipolar disorder

I. Bonis, J.A. Santas, Benito Morentín, Luís F. Callado, J. Javier Meana, Elisabet Vilella, Alfredo Ramos‐Miguel, Guadalupe Rivero   +7 more
openalex   +1 more source

Upregulated spinal histone deacetylases induce nociceptive sensitization by inhibiting the GABA system in chronic constriction injury-induced neuropathy in rats. [PDF]

Pain Rep
Wen ZH, Chen NF, Cheng HJ, Kuo HM, Chen PY, Feng CW, Yao ZK, Chen WF, Sung CS.   +8 more
europepmc   +1 more source

Investigating Potential Cancer Therapeutics: Insight into Histone Deacetylases (HDACs) Inhibitions. [PDF]

Pharmaceuticals (Basel)
Ahmad B, Saeed A, Al-Amery A, Celik I, Ahmed I, Yaseen M, Khan IA, Al-Fahad D, Bhat MA.   +8 more
europepmc   +1 more source

Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets. [PDF]

J Crohns Colitis
Lewis A, Humphreys DT, Pan-Castillo B, Berti G, Felice C, Gordon H, Gadhok R, Nijhuis A, Mehta S S, Eleid L, Iqbal S, Armuzzi A, Minicozzi A, Giannoulatou E, ChinAleong J, Feakins R, Sagi-Kiss V, Barisic D, Koufaki MI, Bundy JG, Lindsay JO, Silver A.   +21 more
europepmc   +1 more source

Additional file 2 of Histone deacetylase HDAC7 restricts CD8 + T cell tumor infiltration and limits immunotherapy sensitivity in bladder cancer: reversal by pinocembrin

Jiancheng Lv, Kai Li, Jiatong Zhou, Ruixi Yu, Qiang Lu, B. Liu   +5 more
openalex   +1 more source

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Histone deacetylases

Current Opinion in Pharmacology, 2003
Post-translational modification of the histones of chromatin has a fundamental role in regulating gene expression. Enzymes involved in these epigenetic events include histone deacetylases (class I and class II), which can be inhibited by a structurally diverse group of small molecules.
Paul A, Marks, Thomas, Miller, Victoria M, Richon   +2 more
openaire   +2 more sources

Histone Deacetylase Inhibitors

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Thomas A, Miller, David J, Witter, Sandro, Belvedere   +2 more
openaire   +2 more sources

Histone Deacetylases

2008
Deacetylation of histones is required for gene regulation and cell cycle progression and the mediators, the histone deacetylases, are being vigorously pursued as drug targets for cancer chemotherapy. The deacetylases are also potential drug targets against infectious diseases and genome sequencing revealed proteins of this class in each of three ...
  +6 more sources