Results 141 to 150 of about 28,454 (236)

Histone demethylase PHF2 regulates inflammatory genes in Alzheimer's disease. [PDF]

Mol Psychiatry
Yang G, Ren Y, Zhong P, Patel PJ, Chen XQ, Wan L, Lee YH, Saleem K, Feng J, Yan Z.   +9 more
europepmc   +1 more source

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic, Megan Wynalda, Montserrat C. Anguera   +2 more
wiley   +1 more source

The role of histone demethylase PHF2 as a tumour suppressor in hepatocellular carcinoma by regulating SRXN1. [PDF]

Oncogenesis
Thng DKH, Hooi L, Yong WK, Kappei D, Toh TB, Chow EK.   +5 more
europepmc   +1 more source

Sex‐Specific Factors Influencing HIV Infection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Immune responses are key in controlling viral infections such as HIV‐1, which remains a global challenge to public health. X/Y‐chromosome‐encoded genes and sex steroid hormones can modulate immune cells and drive distinct patterns of gene and protein expression involved in antiviral function, impacting sex‐dependent immune responses and ...
Maria Pujantell, Marcus Altfeld
wiley   +1 more source

Losing is the new winning: loss of histone demethylase DT2 enhances drought stress tolerance in rice. [PDF]

Plant Physiol
Sharma G.
europepmc   +1 more source

Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning, Balagopal Pai, Maike Collienne, Isabel Ben‐Batalla, Sonja Loges   +4 more
wiley   +1 more source

IL-17A is increased in diabetic wounds and impairs keratinocyte function via histone demethylase JMJD3. [PDF]

Nat Commun
Moon JY, Wolf SJ, Joshi AD, Zhang H, Shadiow J, Bauer TM, Mangum KD, Hughes LD, Audu CO, Melvin WJ, Barrett EC, Rocco S, de Jimenez GS, Estor AL, Nelapudi M, Li Q, Bogle R, Levi B, Davis FM, Obi AT, Moore BB, Tsoi LC, Gudjonsson JE, Gallagher KA.   +23 more
europepmc   +1 more source

Sex Differences in Metabolite–Immune Circuits of Neuroinflammation

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan, Maija Corey, Alicia Gibbons, Mahati Rayadurgam, Neha Reddy, Pavithra Ramesh, Sonia Sharma   +6 more
wiley   +1 more source

Anti-tumor effects and mechanism of the histone demethylase inhibitor GSK-J4 in non-small cell lung cancer cells. [PDF]

Med Oncol
Xu D, Wang M, Wu M, Yu Y, Chen X, Wen Z, Shen D, Liu T, Chen H.   +8 more
europepmc   +1 more source

Transposable element‐mediated DNA methylation of the NAC20 and NAC26 promoters led to a maternal effect on grain filling

Journal of Integrative Plant Biology, Volume 68, Issue 3, Page 828-840, March 2026.
The rice transcription factor genes NAC20 and NAC26 regulate grain filling and show allele‐specific maternal expression due to transposable element insertions and paternal hypermethylation in their 5' upstream regions. Geographical analyses showed that japonica varieties that originated at high latitudes carried these transposable elements.
Ming‐Wei Wu, Rong Li, Wen‐Tao Wei, Meng‐Meng Chen, Jin‐Lei Liu, Han Cheng, Tao Yang, Jin‐Dan Zhang, Jinxin Liu, Chun‐Ming Liu   +9 more
wiley   +1 more source