Results 141 to 150 of about 166,151 (260)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Methyl-CpG-binding protein 2 reads histone methylation via an aromatic cage to regulate gene expression and chromatin association. [PDF]

J Biol Chem
Padhan J, Sudhamalla B.
europepmc   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

PRMT5 upregulates KCNMB4 expression via histone methylation to promote paclitaxel resistance in advanced nasopharyngeal carcinoma. [PDF]

Cell Death Dis
Liu L, Liu S, Wang Y, Wang P, Zhong G, Hong JH, Xiao R, Guo Y, Zhu F, Hao J, Chen J, Mai HQ, Tan J.   +12 more
europepmc   +1 more source

Forecasting histone methylation by Polycomb complexes with minute-scale precision. [PDF]

Sci Adv, 2023
Lundkvist MJ, Lizana L, Schwartz YB.
europepmc   +1 more source

Human opsin restoration by histone methylation using methyltransferase fusion protein SETD7-dCas9. [PDF]

Mol Ther Nucleic Acids
Tran NL, Kang YE, Jeong H, Kim Y, Shin SC, Kim SH, Park B, Oh SJ.   +7 more
europepmc   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source

Distinct classes of lamina-associated domains are defined by differential patterns of repressive histone methylation. [PDF]

Genome Res
Martin CJ, Oser EA, Nagarajan P, Popova LV, Sunkel BD, Stanton BZ, Parthun MR.   +6 more
europepmc   +1 more source

High‐Throughput Geocoding to Assess Short‐Term Air Pollution in Correlation With Mortality in a French Cancer Patient Cohort

International Journal of Cancer, EarlyView.
Although chronic air pollution exposure is linked to lung cancer mortality, the short‐term effects of fluctuating air quality on overall cancer mortality remain uncertain. Here, the authors applied geomatics and machine‐learning models to retrospectively examine possible associations between 31‐day pollution exposure and mortality in a French cancer ...
Loice Pokam, Joséphine Bocquet, Nadia Hégarat, Julie Perlbarg‐Samson, Thomas Balezeau, Maud Milder, Bastien Rance, Hector Countouris, Julien Guerin, Flavien Gilles, Jean Gaudart, Nicolas Girard, Clémence Basse   +12 more
wiley   +1 more source

Ectopic transcription due to inherited histone methylation may interfere with the ongoing function of differentiated neurons. [PDF]

Proc Natl Acad Sci U S A
Rodriguez JD, Reeves MN, Chavez SR, Wang HV, Chavez JZ, Rastogi R, Sun LI, Roberson MS, Preston EA, Massenburg Z, Cruz KN, Chadha MS, Hill EJ, Soares ML, Corces VG, Carpenter BS, Schmeichel KL, Murray JI, Katz DJ.   +18 more
europepmc   +1 more source