Results 11 to 20 of about 186,634 (241)
Histone Octamer Transfer by a Chromatin-Remodeling Complex [PDF]
Cell, 1999 RSC, an abundant, essential chromatin-remodeling complex related to SWI/SNF complex, catalyzes the transfer of a histone octamer from a nucleosome core particle to naked DNA. The newly formed octamer-DNA complex is identical with a nucleosome in all respects. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. The mechanism
Yahli Lorch +2 more
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Epigenetics & Chromatin, 2012 Background The protein anti-silencing function 1 (Asf1) chaperones histones H3/H4 for assembly into nucleosomes every cell cycle as well as during DNA transcription and repair.
Chavez Myrriah S +5 more
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Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair. [PDF]
J Biol Chem, 2017 Repair of DNA double strand breaks (DSBs) is key for maintenance of genome integrity. When DSBs are repaired by homologous recombination, DNA ends can undergo extensive processing, producing long stretches of single-stranded DNA (ssDNA).
Adkins NL +7 more
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Histone Octamer Structure Is Altered Early in ISW2 ATP-Dependent Nucleosome Remodeling
Cell Reports, 2019 Summary: Nucleosomes are the fundamental building blocks of chromatin that regulate DNA access and are composed of histone octamers. ATP-dependent chromatin remodelers like ISW2 regulate chromatin access by translationally moving nucleosomes to different
Arjan Hada +10 more
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Points of contact between histone H1 and the histone octamer. [PDF]
Proceedings of the National Academy of Sciences, 1980 The topography of the interaction between histone H1 and the histone octamer has been investigated. Bovine thymus nuclei or enzymatically fragmented chromatin were treated 1-ethyl-3(3-dimethylaminopropyl)carbodiimide, which catalyzes the formation of covalent bonds between residues of proteins in electrostatic contact.
T. Boulikas, J. Wiseman, W. Garrard
semanticscholar +3 more sources
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions. [PDF]
Mol Cell, 2023 Donovan BT +7 more
europepmc +4 more sources
A Histone Octamer Blocks Branch Migration of a Holliday Junction [PDF]
Molecular and Cellular Biology, 1997 The Holliday junction is a key intermediate in genetic recombination. Here, we examine the effect of a nucleosome core on movement of the Holliday junction in vitro by spontaneous branch migration. Histone octamers consisting of H2A, H2B, H3, and H4 are reconstituted onto DNA duplexes containing an artificial nucleosome-positioning sequence consisting ...
Mikhaïl Grigoriev, Peggy Hsieh
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Isolation of the yeast histone octamer. [PDF]
Proceedings of the National Academy of Sciences, 1994 Procedures for the extraction and purification of the yeast histone octamer are described. Either mechanical disruption, yielding chromatin fragments, or spheroplast formation with subsequent nuclear isolation was employed. A hexahistidine tag was inserted in the N-terminal region of histone H2B, permitting resolution of the histone octamer from high ...
Y. Lorch, R. Kornberg
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Heterogeneous assembly of nascent core histones to form nucleosomal histone octamers in mouse FM3A cells [PDF]
European Journal of Biochemistry, 1989 We investigated the assembly of newly synthesized histones into nucleosomal histone octamers using an isopycnic centrifugation analysis of these proteins of mouse FM3A cells that had been labeled by culture with heavy amino acids. Cross‐linked histone octamers or non‐cross‐linked core histones were separated electrophoretically from other proteins on ...
Kaoru Sugasawa +4 more
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High Energy Radiation-Induced Crosslinking of Histone Octamer Complexes [PDF]
Zeitschrift für Naturforschung C, 1984 Abstract Calf thymus histone octamer complexes were irradiated in the native state in N2O-saturated dilute aqueous solution (0.5 g/l, pH 9, [NaClO4] = 1-4 mol/1) with 50 or 100 ns pulses of 16 MeV electrons or 60Co-γ-rays. Tim e resolved light scattering measurem ents and optical absorption measurements yielded the following: the ...
K.-J. Deeg, Lynne Katsikas, W. Schnabel
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