Results 31 to 40 of about 50 (49)
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A histone octamer-like structure within TFIID
Nature, 1996The general transcription factor TFIID nucleates initiation complex formation through direct core promoter binding, commits promoters within chromatin to transcription, and mediates the action of transcriptional activators, a phenomenon that may correlate with enhanced TFIID recruitment or conformational changes in TFIID-promoter complexes.
Robert G. Roeder +8 more
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Mathematical modeling the formation of a histone octamer
Technical Physics, 2017A physical model of the interaction of protein molecules and their ability to form complex biological systems for the in vitro case in a solution of monovalent salt has been developed. Their reactive abilities using the methods of electrostatics based on the example of the step-by-step formation of the histone octamer from the H2A, H2B, H3, and H4 ...
Tatiana Koshlan, K. G. Kulikov
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The identity of conformational states of reconstituted and native histone octamers
European Journal of Biochemistry, 1983Histone octamers were reconstituted from the following preparations: (a) natural histone H3‐H4 tetramer and histone H2A‐H2B dimer, either selectively extracted from chromatin with solutions of sodium chloride or prepared by dissociation of the natural octamer; (b) acid‐denatured core histones, either an unfractionated mixture or individually purified ...
B T Sewell +3 more
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ESR studies of γ-irradiated histone octamer and the histone H3
Radiation Physics and Chemistry, 1998Abstract ESR spectrum of neat histone H3 γ -irradiated and observed at 77 K with low microwave power and modulation amplitude showed multiple resolved structure depicting nonequivalent interaction of the unpaired electron located at amido-carbonyl radical anion [– CHR C ( O − )NH–] of the peptide backbone with adjacent –NH– group and ...
Tiecheng Tu +4 more
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Energetics and Affinity of the Histone Octamer for Defined DNA Sequences
Biochemistry, 2001Previous studies have compared the relative free energies for histone octamer binding to various DNA sequences; however, no reports of the equilibrium binding affinity of the octamer for unique sequences have been presented. It has been shown that nucleosome core particles (NCPs) dissociate into free DNA and histone octamers (or free histones) on ...
Joel M. Gottesfeld, Karolin Luger
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Spectropolarimetric analysis of the core histone octamer and its subunits
Biochemistry, 1990The secondary structure of the calf thymus core histone octamer, (H2A-H2B-H3-H4)2, and its two physiological subunits, the H2A-H2B dimer and (H3-H4)2 tetramer, was analyzed by ORD spectropolarimetry as a function of temperature and solvent ionic strength within the ranges of these experimental parameters where assembly of the core histone octamer ...
Evangelos N. Moudrianakis +2 more
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Reassembly of Nucleosomal Histone Octamers during Replication of Chromatin1
The Journal of Biochemistry, 1987We have examined critically whether or not new and old histones mix in the octameric units of nucleosomes during chromatin replication. MH-134SC cells were density-labeled by culturing with amino acid mixtures enriched with dense isotopes 2H, 13C, and 15N. Mononucleosomes obtained from labeled cells were fractionated by rate zonal sedimentation through
Kyo Yamasu, Tatsuo Senshu
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[23] Algorithms for prediction of histone octamer binding sites
1992Publisher Summary This chapter presents algorithms for the prediction of histone octamer binding sites. Methods for the prediction of preferred binding sites for the histone octamer on a defined DNA sequence are of two types. In statistically based algorithms, the tested sequences are compared against the sequence organization of experimentally ...
Travers Aa, Turnell Wg
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Enhanced stability of histone octamers from plant nucleosomes: Role of H2A and H2B histones [PDF]
Biochemistry, 1992 Gel filtration and sedimentation studies have previously established that the vertebrate animal core histone octamer is in equilibrium with an (H3-H4)2 tetramer and an H2A-H2B dimer [Eickbush, T. H., & Moudrianakis, E. N. (1978) Biochemistry 17, 4955-4964; Godfrey, J. E., Eickbush, T. H., & Moudrianakis, E. N. (1980) Biochemistry 19, 1339-1346].
Andreas D. Baxevanis +3 more
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Structural analysis of a reconstituted DNA containing three histone octamers and histone H5
Journal of Molecular Biology, 1987Previous work has shown that DNA and the histone proteins will combine to form structures of a complex, yet definite nature. Here, we describe three experiments aimed at a better understanding of the interactions of DNA with the histone octamer and with histone H5. First, there has been some question as to whether the methylation of DNA could influence
Maxine J. McCall, Horace R. Drew
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