Results 121 to 130 of about 8,454 (206)

Independent evolutionary origin of histone H3.3-like variants of animals and Tetrahymena

Nucleic Acids Research, 1994
All three genes encoding histone H3 proteins were cloned and sequenced from Tetrahymena thermophila. Two of these genes encode a major H3 protein identical to that of T. pyriformis and 87% identical to the major H3 of vertebrates. The third gene encodes hv2, a quantitatively minor replication independent (replacement) variant.
T H, Thatcher, J, MacGaffey, J, Bowen, S, Horowitz, D L, Shapiro, M A, Gorovsky   +5 more
openaire   +3 more sources

Comparing the Assembly and Handedness Dynamics of (H3.3-H4)2 Tetrasomes to Canonical Tetrasomes.

PLoS ONE, 2015
Eukaryotic nucleosomes consists of an (H3-H4)2 tetramer and two H2A-H2B dimers, around which 147 bp of DNA are wrapped in 1.7 left-handed helical turns.
Rifka Vlijm, Mina Lee, Orkide Ordu, Anastasiya Boltengagen, Alexandra Lusser, Nynke H Dekker, Cees Dekker   +6 more
doaj   +1 more source

Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity. [PDF]

Proc Natl Acad Sci U S A, 2022
Funk OH, Qalieh Y, Doyle DZ, Lam MM, Kwan KY.   +4 more
europepmc   +1 more source

Transposable Elements, Inflammation, and Neurological Disease. [PDF]

, 2019
Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela, Muotri, Alysson R, Saleh, Aurian   +2 more
core  

Two distinct modes for propagation of histone PTMs across the cell cycle [PDF]

, 2015
Epigenetic states defined by chromatin can be maintained through mitotic cell division. However, it remains unknown how histone-based information is transmitted.
Alabert, Constance, Barth, Teresa K., Groth, Anja, Imhof, Axel, Jensen, Olen, Reverón-Gómez, Nazaret, Schmidt, Andreas, Sidoli, Simone   +7 more
core   +2 more sources

Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability. [PDF]

Nat Cell Biol, 2022
Guo P, Liu Y, Geng F, Daman AW, Liu X, Zhong L, Ravishankar A, Lis R, Barcia Durán JG, Itkin T, Tang F, Zhang T, Xiang J, Shido K, Ding BS, Wen D, Josefowicz SZ, Rafii S.   +17 more
europepmc   +1 more source

Epigenetic regulation of centromeric chromatin: old dogs, new tricks? [PDF]

, 2008
The assembly of just a single kinetochore at the centromere of each sister chromatid is essential for accurate chromosome segregation during cell division.
A Aguilera, A Alonso, AG Castillo, AL Lam, AR Mitchell, AW Lo, B Li, B Sullivan, BA Sullivan, BA Sullivan, BA Sullivan, BA Sullivan, BA Weaver, BC Williams, BE Black, BE Black, BE Black, BG Mellone, BJ Buchwitz, BP May, C Polizzi, CG Pearson, CL Rieder, CN Topp, CW Carroll, D Reinberg, D Vermaak, DK Palmer, DR Foltz, E Yeh, EM Dunleavy, ES Chen, ES Chen, G Mizuguchi, G Mizuguchi, Gary H. Karpen, GH Karpen, H Bouzinba-Segard, H Izuta, H Tagami, H Yan, H Yan, HD Folco, HP Cam, HS Malik, I Grummt, IK Greaves, J Gregan, J Walfridsson, JA Mello, JJ Harrington, JM Sogo, JM Spence, K Ahmad, K Ahmad, K Ishii, K Sugasawa, K Takahashi, K Takahashi, K Yoda, KA Maggert, KC Keith, KF Sullivan, KH Choo, KM Hahnenberger, KV Bulazel, L Clarke, LE Jansen, LH Wong, M Agudo, M Baum, M Buhler, M Ikeno, M Nakano, M Okada, M Schuh, MD Blower, MD Blower, MD Meneghini, N Conde e Silva, NC Steiner, P Heun, P Neumann, PB Meluh, PE Warburton, PE Warburton, PS Maddox, R Camahort, R Saffery, R Saffery, RD Shelby, RD Shelby, RK Dawe, RM Raisner, Robin C. Allshire, S Furuyama, S Henikoff, S Henikoff, S Henikoff, S Rea, S Saitoh, S Stoler, S Stoler, S Westermann, SG Zeitlin, SI Grewal, SK Williams, SM Kim, SR Carlson, T Furuyama, T Hassold, T Hayashi, T Jenuwein, T Kouzarides, T Maruyama, T Okada, TD Murphy, W Rocha, WC Earnshaw, Y Dalal, Y Fujita, Y Mito, Y Takayama, Y Takayama, ZL Monaco   +124 more
core   +1 more source

The HIRA complex that deposits the histone H3.3 is conserved in Arabidopsis and facilitates transcriptional dynamics

Biology Open, 2014
In animals, replication-independent incorporation of nucleosomes containing the histone variant H3.3 enables global reprogramming of histone modifications and transcriptional profiles.
Xin Nie, Haifeng Wang, Jing Li, Sarah Holec, Frédéric Berger   +4 more
doaj   +1 more source

Multi-omic profiling of histone variant H3.3 lysine 27 methylation reveals a distinct role from canonical H3 in stem cell differentiation. [PDF]

Mol Omics, 2022
Kori Y, Lund PJ, Trovato M, Sidoli S, Yuan ZF, Noh KM, Garcia BA.   +6 more
europepmc   +1 more source

Novel improvement in iPSCs generation protocols through mouse gametogenesis epigenetic erasure mechanisms [PDF]

, 2016
The main goal of this review is to describe gametogenesis epigenetic erasure mechanisms and to propose candidate molecules which can erase remaining epigenetic marks that enhace re-differentiation of cultured induced pluripotent stem cells (iPSCs) into ...
Díaz Pedrosa, Núria, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
core