Results 41 to 50 of about 8,454 (206)

Conservation of centromeric histone 3 interaction partners in plants [PDF]

, 2020
The loading and maintenance of centromeric histone 3 (CENH3) at the centromere are critical processes ensuring appropriate kinetochore establishment and equivalent segregation of the homologous chromosomes during cell division.
Geelen, Danny, Jin, Chunlian, Keçeli, Burcu Nur, Van Damme, Daniël   +3 more
core   +1 more source

Histone H3 methylation orchestrates transcriptional program in mouse spermatogenic cell line

The Journal of Reproduction and Development, 2020
Changes in histone modifications always correlate with altered transcriptional activities of genes. Recent studies have shown that the mutation of certain lysine residues to methionine in the histone variant H3.3 can act as a valuable tool to reduce ...
Xiao-fei WANG, Qing TIAN, Wei-bing QIN, Ying YIN, Ling ZENG, Yun-ge TANG, Ping SU, Li-quan ZHOU   +7 more
doaj   +1 more source

Auxin and epigenetic regulation of SKP2B, an F-box that represses lateral root formation [PDF]

, 2012
In plants, lateral roots originate from pericycle founder cells that are specified at regular intervals along the main root. Here, we show that Arabidopsis (Arabidopsis thaliana) SKP2B (for S-Phase Kinase-Associated Protein2B), an F-box protein ...
Beeckman, Tom, Casero, Pedro, Casimiro, Ilda, De Rybel, Bert, del Pozo, Juan C, Desvoyes, Bénédicte, Gutierrez, Crisanto, Manzano, Concepción, Otero, Sofía, Ramirez-Parra, Elena   +9 more
core   +2 more sources

A Drosophila melanogaster H3.3 cDNA encodes a histone variant identical with the vertebrate H3.3

Gene, 1991
A cDNA encoding an H3.3 histone variant in Drosophila melanogaster predicts a protein with an amino acid (aa) sequence identical with that in vertebrates. The D. melanogaster H3.3 nucleotide (nt) sequence has diverged significantly from that of both the H3.3 gene of vertebrates and the H3.1 gene of D.
Fretzin, Scott, Allan, Barbara D., van Daal, Angela, Elgin, Sarah C.R.   +3 more
openaire   +4 more sources

Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements

iScience, 2020
Summary: Replication-dependent canonical histone messenger RNAs (mRNAs) do not terminate with a poly(A) tail at the 3′ end. We previously demonstrated that exposure to arsenic, an environmental carcinogen, induces polyadenylation of canonical histone H3 ...
Danqi Chen, Qiao Yi Chen, Zhenjia Wang, Yusha Zhu, Thomas Kluz, Wuwei Tan, Jinquan Li, Feng Wu, Lei Fang, Xiaoru Zhang, Rongquan He, Steven Shen, Hong Sun, Chongzhi Zang, Chunyuan Jin, Max Costa   +15 more
doaj   +1 more source

Replication-Uncoupled Histone Deposition during Adenovirus DNA Replication [PDF]

, 2012
In infected cells, the chromatin structure of the adenovirus genome DNA plays critical roles in its genome functions. Previously, we reported that in early phases of infection, incoming viral DNA is associated with both viral core protein VII and ...
Komatsu Tetsuro, Nagata Kyosuke, 小松 哲郎, 永田 恭介   +3 more
core   +1 more source

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions [PDF]

Cell, 2010
The incorporation of histone H3 variants has been implicated in the epigenetic memory of cellular state. Using genome editing with zinc-finger nucleases to tag endogenous H3.3, we report genome-wide profiles of H3 variants in mammalian embryonic stem cells and neuronal precursor cells.
Goldberg AD, Banaszynski LA, Noh KM, Lewis PW, Elsaesser SJ, Stadler S, Dewell S, Law M, Guo X, Li X, Wen D, Chapgier A, DeKelver RC, Miller JC, Lee YL, Boydston EA, Holmes MC, Gregory PD, Greally JM, Rafii S, Yang C, Scambler PJ, Garrick D, Gibbons RJ, Higgs DR, Cristea IM, Urnov FD, Zheng D, Allis CD   +28 more
openaire   +3 more sources

Biophysical characterization of histone H3.3 K27M point mutation [PDF]

, 2018
K
Boros-Oláh, Beáta, Hetey, Szabolcs, Karányi, Zsolt, Kuik-Rózsa, Tímea, Li, Qiuzhen, Roszik, Jason, Szabó, Zoltán, Szalóki, Nikoletta, Székvölgyi, Lóránt, Tóth, Katalin Ágnes, Vámosi, György   +10 more
core   +1 more source

H3.3 contributes to chromatin accessibility and transcription factor binding at promoter-proximal regulatory elements in embryonic stem cells

Genome Biology, 2023
Background The histone variant H3.3 is enriched at active regulatory elements such as promoters and enhancers in mammalian genomes. These regions are highly accessible, creating an environment that is permissive to transcription factor binding and the ...
Amanuel Tafessu, Ryan O’Hara, Sara Martire, Altair L. Dube, Purbita Saha, Vincent U. Gant, Laura A. Banaszynski   +6 more
doaj   +1 more source

Distinct chromatin signature of histone H3 variant H3.3 in human cells [PDF]

Nucleus, 2014
Actively transcribed regions of the genome have been found enriched for the histone H3 variant H3.3. This variant is incorporated into nucleosomes throughout the cell cycle whereas the canonical isoforms are predominately deposited in association with replication. In order to obtain a global picture of the deposition pattern at the single cell level we
Snyers, Luc, Zupkovitz, Gordin, Almeder, Marlene, Fliesser, Marianne, Stoisser, Anja, Weipoltshammer, Klara, Schöfer, Christian   +6 more
openaire   +2 more sources