Results 171 to 180 of about 317,398 (334)

THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATION

, 1967
Elliott Robbins, Thaddeus W. Borun
openalex   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source

Kringle-Dependent Inhibition of Plasmin-Mediated Fibrinolysis by Native and Citrullinated Core Histones. [PDF]

Int J Mol Sci
Komorowicz E, Gurabi A, Wacha A, Szabó L, Ozohanics O, Kolev K.   +5 more
europepmc   +1 more source

Turnover of template-bound histone.

, 1965
G. Roger Chalkley, H. R. Maurer
openalex   +1 more source

A unique binding mode enables MCM2 to chaperone histones H3–H4 at replication forks

Nature Structural &Molecular Biology, 2015
Hongda Huang, Caroline B Strømme, Giulia Saredi, Martina Hödl, A. Strandsby, Cristina González-Aguilera, Shoudeng Chen, Anja Groth, D. Patel   +8 more
semanticscholar   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Insights into the synchronization between DNA replication and parental histone recycling. [PDF]

Biochem Soc Trans
Tang X, Yao Y, Li G, Gan H.
europepmc   +1 more source

The Histones

, 1962
D. M. P. Phillips
openalex   +1 more source

Histones link inflammation and thrombosis through the induction of Weibel–Palade body exocytosis

Journal of Thrombosis and Haemostasis, 2016
A. Michels, S. Albánez, J. Mewburn, K. Nesbitt, T. J. Gould, P. Liaw, P. James, L. Swystun, D. Lillicrap   +8 more
semanticscholar   +1 more source

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source