Results 201 to 210 of about 245,589 (335)

Restoration of Transforming Growth Factor-β Signaling through Receptor RI Induction by Histone Deacetylase Activity Inhibition in Breast Cancer Cells [PDF]

, 2004
Sudhakar Ammanamanchi, Michael G. Brattain   +1 more
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Equine histones are mobilized within equid alphaherpesvirus 1 (EHV1) replication compartments. [PDF]

J Virol
Conn KL.
europepmc   +1 more source

Total Protein, Deoxyribonucleic Acid, Ribonucleic Acid, and Histone Content of Isolated Nuclei of Chicken Erythrocytes

, 1974
R.E. Isaacks, JoséA. Guerrero
openalex   +1 more source

Histone H2B monoubiquitination regulates salt stress‐induced microtubule depolymerization in Arabidopsis [PDF]

, 2017
Sa Zhou, Qiuhong Chen, Yuhui Sun, Yingzhang Li   +3 more
openalex   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

H2A.Z and H3:K56Q Affect Transcription Through Chromatin and Yeast FACT-Dependent Nucleosome Unfolding. [PDF]

Int J Mol Sci
Afonin D, Ukrainets ER, Kotova E, Gerasimova NS, Armeev GA, Kirpichnikov MP, Feofanov AV, Studitsky VM.   +7 more
europepmc   +1 more source

Development of Homogeneous Nonradioactive Methyltransferase and Demethylase Assays Targeting Histone H3 Lysine 4 [PDF]

, 2011
Nancy Gauthier, Mireille Caron, Liliana Pedro, Mathieu Arcand, Julie Blouin, Anne Labonté, Claire Normand, Valérie E. Paquet, Anja Rodenbrock, Marjolaine Roy, Nathalie Rouleau, Lucille Beaudet, Jaime Padrós, Roberto Rodrı́guez-Suárez   +13 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Histone post-translational modifications of Leishmania braziliensis. [PDF]

Sci Data
de Almeida RF, Fernandes M, Figueiredo FB, de Godoy LMF.   +3 more
europepmc   +1 more source