Results 291 to 300 of about 245,589 (335)

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Butyrate blocks specific histone acetylation by preventing recruitment of p300 to acetylated histones

Jiang M, Psoma A, Lyu J, Chiariello MG, Modderman R, Bianchi F, Incarnato D, Marrink S, Jonkers IH, van den Bogaart G.   +9 more
europepmc   +1 more source

Faithful inheritance: Parental histone recycling and epigenetic memory in fission yeast. [PDF]

Cell Insight
Fang Y, Toda T, Jia S.
europepmc   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

Neutrophil extracellular traps in rheumatoid arthritis: pathogenic mechanisms and therapeutic potential. [PDF]

Front Immunol
Mao CL, Yu CH, Jiang SL, Ying ZH, Zhu XY.   +4 more
europepmc   +1 more source

Structural Variation and 3D Genome‐Driven DNA/RNA Methylation Divergence Contributing to Cotton Fiber Domestication

Advanced Science, EarlyView.
These findings elucidated the crucial role of the “SVs‐3D genome remodeling‐epigenetic modifications‐gene expression” cascade regulatory network in cotton fiber domestication, offering both a theoretical foundation and genetic resources for molecular design breeding in fiber crops.
Lei Shao, Shangkun Jin, Haojie Jiang, Tianyu Pan, Zesheng Rui, Xiaowen Shi, Ting Zhao, Zhanfeng Si, Xueying Guan, Yan Hu, Tianzhen Zhang, Lei Fang   +11 more
wiley   +1 more source

Histone-driven hypercoagulation contributes to the lethal triad of acute trauma-induced coagulopathy. [PDF]

Sci Rep
Braun CK, Mannes M, Spiegelburg DT, Müller F, Klitzing A, Schultze A, Bauer A, Achatz G, Huber-Lang M.   +8 more
europepmc   +1 more source

Molecular Mechanisms and Therapeutic Potential of Baicalein in Acute Pancreatitis: A Comprehensive Review. [PDF]

Biomolecules
Yao L, Liu S, Huang W, Yang X.
europepmc   +1 more source

NETosis-specific cell death: a novel mechanism in the pathogenesis of gouty arthritis. [PDF]

Eur J Med Res
Liu K, Ma S, Li D, Wang M, Zhao H, Song Z, Su M, Meng Q, Zhou Z.   +8 more
europepmc   +1 more source

Interaction of Carbon Dots with Nucleic Acids Is Driven by Their Surface Charge. [PDF]

J Chem Inf Model
Nedělníková A, Stadlbauer P, Banáš P, Šponer J, Otyepka M, Kührová P, Paloncýová M.   +6 more
europepmc   +1 more source