Results 71 to 80 of about 256,649 (274)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

EPIIC: Edge-Preserving Method Increasing Nuclei Clarity for Compression Artifacts Removal in Whole-Slide Histopathological Images

open access: yesApplied Sciences
Hematoxylin and eosin (HE) staining is widely used in medical diagnosis. Stained slides provide crucial information to diagnose or monitor the progress of many diseases.
Julia Merta, Michal Marczyk
doaj   +1 more source

Data for glomeruli characterization in histopathological images

open access: yesData in Brief, 2020
The data presented in this article is part of the whole slide imaging (WSI) datasets generated in European project AIDPATH 2 This data is also related to the research paper entitle “Glomerulosclerosis Identification in Whole Slide Images using Semantic ...
Gloria Bueno   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Advancing Prostate Cancer Diagnostics: A ConvNeXt Approach to Multi-Class Classification in Underrepresented Populations

open access: yesBioengineering
Prostate cancer is a leading cause of cancer-related morbidity and mortality worldwide, with diagnostic challenges magnified in underrepresented regions like sub-Saharan Africa.
Declan Ikechukwu Emegano   +4 more
doaj   +1 more source

Evaluation and treatment decision of pancreatic tumors by use of MRI with MRCP imaging [PDF]

open access: yes, 2009
Background: Pancreatic cancer is one of the most malignant tumors. Symptoms are usually nonspecific and insidious such that the cancer is advanced by the time of diagnosis.
Turowska, Aldona   +2 more
core  

Difficulty Translation in Histopathology Images [PDF]

open access: yes, 2020
The unique nature of histopathology images opens the door to domain-specific formulations of image translation models. We propose a difficulty translation model that modifies colorectal histopathology images to be more challenging to classify. Our model comprises a scorer, which provides an output confidence to measure the difficulty of images, and an ...
Wei, Jerry   +7 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Attention-Based DenseNet for Lung Cancer Classification Using CT Scan and Histopathological Images

open access: yesDesigns
Lung cancer is identified by the uncontrolled proliferation of cells in lung tissues. The timely detection of malignant cells in the lungs, crucial for processes such as oxygen provision and carbon dioxide elimination in the human body, is imperative ...
Jia Uddin
doaj   +1 more source

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