Results 71 to 80 of about 259,250 (296)

The Devil is in the Details: Whole Slide Image Acquisition and Processing for Artifacts Detection, Color Variation, and Data Augmentation: A Review

IEEE Access, 2022
Whole Slide Images (WSI) are widely used in histopathology for research and the diagnosis of different types of cancer. The preparation and digitization of histological tissues leads to the introduction of artifacts and variations that need to be ...
Neel Kanwal, Fernando Perez-Bueno, Arne Schmidt, Kjersti Engan, Rafael Molina   +4 more
doaj   +1 more source

The symptomatology of aneurysmal bone cyst : the value of diagnostic imaging [PDF]

, 2009
Background: An aneurysmal bone cyst (ABC) is a benign lesion occurring mainly in children. Generally it is found in the metaphyses of long bones and in flat bones.
Bekiesińska-Figatowska, Monika, Brągoszewska, Hanna, Iwanowska, Beata, Klepacka, Teresa, Kopyś-Wiszniewska, Izabela, Kowalska, Barbara, Koziarska, Teresa, Romaniuk-Doroszewska, Anna, Rychłowska-Pruszyńska, Magdalena, Uliasz, Maria   +9 more
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Spider venom administration impairs glioblastoma growth and modulates immune response in a non-clinical model. [PDF]

, 2020
Molecules from animal venoms are promising candidates for the development of new drugs. Previous in vitro studies have shown that the venom of the spider Phoneutria nigriventer (PnV) is a potential source of antineoplastic components with activity in ...
Barreto, Natália, Bonfanti, Amanda Pires, Brunetto, Sérgio, Caballero, Marcus, Cordeiro, Gabriel, Moura, Fernanda, Munhoz, Jaqueline, Ramos, Celso Dario, Rapôso, Catarina, Rocha-E-Silva, Thomaz, Sutti, Rafael, Thome, Rodolfo, Verinaud, Liana   +12 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Difficulty Translation in Histopathology Images [PDF]

, 2020
The unique nature of histopathology images opens the door to domain-specific formulations of image translation models. We propose a difficulty translation model that modifies colorectal histopathology images to be more challenging to classify. Our model comprises a scorer, which provides an output confidence to measure the difficulty of images, and an ...
Wei, Jerry, Suriawinata, Arief, Liu, Xiaoying, Ren, Bing, Nasir-Moin, Mustafa, Tomita, Naofumi, Wei, Jason, Hassanpour, Saeed   +7 more
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

EPIIC: Edge-Preserving Method Increasing Nuclei Clarity for Compression Artifacts Removal in Whole-Slide Histopathological Images

Applied Sciences
Hematoxylin and eosin (HE) staining is widely used in medical diagnosis. Stained slides provide crucial information to diagnose or monitor the progress of many diseases.
Julia Merta, Michal Marczyk
doaj   +1 more source

Evaluation and treatment decision of pancreatic tumors by use of MRI with MRCP imaging [PDF]

, 2009
Background: Pancreatic cancer is one of the most malignant tumors. Symptoms are usually nonspecific and insidious such that the cancer is advanced by the time of diagnosis.
Turowska, Aldona, Walecki, Jerzy, Łebkowska, Urszula   +2 more
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