Results 91 to 100 of about 1,368,556 (344)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Digital Archaeological Heritage: an introduction

open access: yesInternet Archaeology, 2017
The 17th EAC Symposium (Europae Archaeologiae Consilium) in Brighton was convened under a concept note that recognised that 'Digital technologies are developing at an unprecedented speed.
Keith May
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Exploring general practice research in Germany: a systematic review of dissertation topics from 1965–2023

open access: yesScandinavian Journal of Primary Health Care
Background Since its academic inception in the 1960s, Germany’s general practice has seen numerous dissertations, many of which are housed in the ‘Archive of German language General Practice’ (ADAM).Aim This study aims to provide the first comprehensive ...
Nora Sosna, Jost Steinhäuser
doaj   +1 more source

Capturing the Material Invisible: OGS Crawford, Ghosts, and the Stonehenge Avenue

open access: yesBulletin of the History of Archaeology, 2016
Why do archaeologists excavate? What should we expect from archaeological archives? OGS Crawford’s discovery and excavation of the course of the Stonehenge Avenue in the summer of 1923 – perhaps the first time that a cropmark was identified on an aerial ...
Martyn Barber
doaj   +1 more source

The Energy Costs of Historic Preservation [PDF]

open access: yes, 2017
We explore the impact of historical preservation policies on domestic energy consumption. Using panel data for England from 2006 to 2013 and employing a fixed effects strategy, we document that (i) rising national energy prices induce an increase in home
Hilber, C., Palmer, C., Pinchbeck, E.
core  

Untangling Historical Injustice and Historical Ill

open access: yes, 2009
Intergenerational Justice Review, Vol 1, No 1 (2009): Historical ...
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Time for "justice" : Research to inform the development of a human rights framework for the design and implementation of an "acknowledgement and accountability forum" on historic abuse of children in Scotland [PDF]

open access: yes, 2009
In 2002, Chris Daly raised a petition to the Scottish Executive (PE535) calling for an independent inquiry into the historic abuse of children in Scotland.
Davidson, Jennifer   +4 more
core  

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