Most excavations in Northern Ireland arise from new development or land-use change proposals. The requirement to mitigate usually results in an excavation of sub-surface remains, with a nuanced approach in dealing with urban, peri-urban and rural sites ...
John D.J. O'Keeffe
doaj +1 more source
The Energy Costs of Historic Preservation [PDF]
We explore the impact of historical preservation policies on domestic energy consumption. Using panel data for England from 2006 to 2013 and employing a fixed effects strategy, we document that (i) rising national energy prices induce an increase in home
Hilber, C., Palmer, C., Pinchbeck, E.
core
Affordances of Historic Urban Landscapes: an Ecological Understanding of Human Interaction with the Past [PDF]
Heritage has been defined differently in European contexts. Despite differences, a common challenge for historic urban landscape management is the integration of tangible and intangible heritage. Integration demands an active view of perception and human-
Alves, Susana
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Digital Archaeological Heritage: an introduction
The 17th EAC Symposium (Europae Archaeologiae Consilium) in Brighton was convened under a concept note that recognised that 'Digital technologies are developing at an unprecedented speed.
Keith May
doaj +1 more source
Hybrid status of honey bee populations near the historic origin of Africanization in Brazil [PDF]
Walter S. Sheppard +3 more
openalex +1 more source
Characterization of immune response against monkeypox virus in cohorts of infected patients, historic and newly vaccinated subjects [PDF]
Josè Camilla Sammartino +10 more
openalex +1 more source
Time for "justice" : Research to inform the development of a human rights framework for the design and implementation of an "acknowledgement and accountability forum" on historic abuse of children in Scotland [PDF]
In 2002, Chris Daly raised a petition to the Scottish Executive (PE535) calling for an independent inquiry into the historic abuse of children in Scotland.
Davidson, Jennifer +4 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source

