Results 91 to 100 of about 55,359 (280)

Pulaski County historic sites photograph collection [DIGITAL CONTENT]

open access: yes
This collection contains photographs related to historic sites in Pulaski ...
Central Arkansas Library System. Butler Center for Arkansas Studies. (Little Rock, Ark.)
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

WEB GIS APPLICATIONS FOR THE HISTORIC SITES

open access: yesHavacılık ve Uzay Teknolojileri Dergisi, 2013
Due to improvements on the technology, web-based Geographic Information Systems become an indispensable part of the projects. Because it provides accessibility, easy usage functions and effective sharing options, it can address to the public people, so ...
Mehmet Alkan   +3 more
doaj  

Preliminary Condition Analysis of Samadhi Dewan Sawan Mal, Multan

open access: yesSir Syed University Research Journal of Engineering and Technology, 2021
Historic structures are unparalleled jewels of the past embedded in the built environment. They integrate the present society with the past and future through its historic fabric existence over the decades.
Jahanzaib Qamar   +2 more
doaj  

The search for historical impact sites on Jupiter

open access: yesPlanetary and Space Science, 1996
Abstract A search was made through historical reports of major dark spots on Jupiter, recorded during the prephotographic era. While many of these reports meet the sufficient condition for impact candidacy (exogenic origin cannot be ruled out), the descriptions and drawings lack the detail required to meet the necessary condition (a morphology ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Historic Markers of Escambia County

open access: yes
This special edition of the magazine details every historic marker in the county. Each marker is represented by an image and transcript.
UWF Historic Trust Publications Staff (author)
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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