Results 141 to 150 of about 194,482 (300)

Reading as a cultural and historical practice

Reading as a cultural and historical practice. A better understanding and use of reading as an academic tool for Indigenous and non-Indigenous students and educators will be a result of the research.

core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Virtual Stonehenge Reconstruction [PDF]

, 2012
Visual and spatial technologies are increasingly revolutionising how archaeology and many other disciplines understand the past in relation to the contemporary world.
Unver, Ertu, Taylor, Andrew
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BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A framework on urban design strategies for sustainability of cultural and historical heritage in urban landscape [PDF]

, 2007
5th WSEAS International Conference on Environment, Ecosystems and Development -- DEC 14-16, 2007 -- Puerto de la Cruz, SPAINCultural heritage is the accumulation of tangible and intangible values stemming from human creativity and interaction between ...
Cetinkale, Sevgi Gormus, Donmez, Sirin, Koçan, Nurhan, Ikiz, Emine, Çelikyay, Hatice Selma, Aydin, Pinar   +5 more
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The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Critical Literacy and Socio-Historical and Cultural theory: approaches and reflections on development and constitution of the subject

, 2022
En este artículo buscamos aproximaciones entre la Teoría Socio-Histórico y Cultural (VYGOTSKY, 2007 [1934]; LURIA, 1988, 2012; MOLON, 2011) y la teoría de la Literacidad (KLEIMAN, 1995, 2006; ROJO, 2009; SOARES, 2003; STREET, 2003, 2014; GEE, 1991, 2000), con énfasis en la Literacidad Crítica (CASSANY; CASTELLÀ, 2010; CARBONIERI, 2016; MENEZES DE SOUZA,
openaire   +1 more source