Results 131 to 140 of about 7,049,835 (311)

A systematic review on spatial-based valuation approach for built cultural heritage [PDF]

open access: yes, 2019
This paper reviews previous research that has been carried out to assess the value of built cultural heritage based on spatial-based valuation approach. Built cultural heritage is classified as a special property and can be categorised under thin market ...
Ismail, Suriatini   +4 more
core  

A tale of two capitalisms: preliminary spatial and historical comparisons of homicide rates in Western Europe and the USA

open access: yes, 2009
This article examines comparative homicide rates in the United States and Western Europe in an era of increasingly globalized neoliberal economics. The main finding of this preliminary analysis is that historical and spatial correlations between distinct
Steve Hall   +3 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Evolution of Cultural Traits Occurs at Similar Relative Rates in Different World Regions

open access: yes, 2014
A fundamental issue in understanding human diversity is whether or not there are regular patterns and processes involved in cultural change. Theoretical and mathematical models of cultural evolution have been developed and are increasingly being used and
Currie, TE, Mace, R
core  

Webinar “Cómic en lenguas indígenas en México”. COST action CA19119 - ICOnMICs

open access: yes, 2023
Focusing on comics in Mexican indigeneous languages, the event chaired by Dr Diana Castilleja (Vrije Universiteit Brussel) brings together authors, specialists and publishers in náhuatl, triqui, hñöhñö and mazahua as part of the lines of investigation of
Castilleja, Diana   +1 more
core  

The pedagogical paradigm "learning to learn" and the historical-cultural approach: contact points

open access: yesRevista MENDIVE, 2008
The objective of this article is to offer the readers an analysis of some common grounds that might exist between the Cultural-Historical Approach and the Pedagogical Paradigm “Learn to Learn”, according to the author’s viewpoints.
Vilma María Pérez Viñas
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Examining teacher education through cultural-historical activity theory

open access: yes
Cultural-historical activity theory (CHAT) is an approach that can be used to analyse human interactions and relationships within particular social contexts.
Wilson, Viv
core  

Essentializing the binary self: individualism and collectivism in cultural neuroscience

open access: yes, 2013
Within the emerging field of cultural neuroscience (CN) one branch of research focuses on the neural underpinnings of “individualistic/Western” vs. “collectivistic/Eastern” self-views.
Marina eMartinez Mateo   +11 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy