Results 121 to 130 of about 198,327 (301)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Response to Commentary “Cultural-Historical Neuropsychology and ADHD” by Prof. Tatiana V. Akhutina

open access: yesКультурно-историческая психология
The present short review contains the authors response to Commentary “Cultural-Historical Neuropsychology and ADHD” by Prof. Tatiana V.
A. Koutsoklenis   +2 more
doaj   +1 more source

Cultural-historical perspective in Spain and Portugal: developing theoretical and methodological approaches

open access: yes, 2019
Cultural-historical research has had a relevant presence in Spain and, to a lesser extent, in Portugal, since the 1970s. A review of the state of the art of the cultural-historical approach in these two countries allows us to identify four general lines ...
García-Perez, Rafael   +11 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

CULTURE UNDER A HISTORICAL-CULTURAL PERSPECTIVE: FIRST APPROACHES

open access: yesTravessias, 2008
 This paper derives from a study developed in a Masters Degree lato sensu course focusing the Historical-Cultural Theory, which was offered by the State University of Maringá-UEM. It is an investigation, in first approach, regarding the meaning of ‘culture’, according to what is postulated by the Historical-Cultural Theory.
openaire   +2 more sources

Integrating agents and virtual institutions for sharing cultural heritage on the Web

open access: yes, 2009
This work outlines the research activities carried out by our groups in the direction of the implementation of a tool for sharing natural and cultural heritage on the web. The tool will serve as a support to teachers and people involved in scientific and
Ancona, Massimo   +7 more
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Historical consciousness and strategies of detraumatization of historical culture in the modern world

open access: yesStudia Humanitatis, 2019
The article presents the socio-philosophical analysis of detraumatization and its main strategies in modern historical culture. Detraumatization was interpreted as the cultural practice of reformatting the semantic structure of relations between the past
Linchenko Andrei Aleksandrovich
doaj  

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