Results 31 to 40 of about 605,182 (304)

Moral and historical consciousness [PDF]

, 2017
In this article I attempt to answer the question - is there is a conceptual link between moral and historical consciousness? I shall first discuss moral concepts and moral development; try to explore what they mean, and what they involve. In doing that
Frímannsson, Gudmundur Heidar
core  

Vernacular Soliloquy, Theatrical Gesture, and Embodied Consciousness in The Marrow of Tradition [PDF]

, 2018
Charles Chesnutt’s Marrow of Tradition (1901) is overwhelmingly understood as an historical novel. Critics have again and again focused on its journalistic historicity; its ambivalent racial politics; its attitudes towards assimilation, separatism ...
Andrews, Andrews, Barnard, Barnard, Bentley, Brook, Brooks, Brown, Brown, Brown, Brown, Caccavari, Carpio, Certeau, Chesnutt, Chesnutt, Chesnutt, Danielson, De Man, De Santis, Delany, Delmar, Delmar, Douglass, Erickson, Finseth, George, Giles, Gilmore, Gleason, Hack, Hardwig, Hebard, Hirsh, Hornsby, Howatson, Ianovici, Kilgore, Knadler, Kurnick, Levine, MacKay, Mariano, Mathewson, McElrath, Moddelmog, Najmi, Nicholas T Rinehart, Pettis, Pickens, Puchner, Rasmussen, Reid-Pharr, Reilly, Roe, Scarry, Shakespeare, Shakespeare, Short, Skiffington, Sollors, Stewart, Sundquist, Sussman, Taylor, Wagner, Wagner-McCoy, Weimann, Wideman, Wideman, Wilson, Wise, Wolkomir, Zogas   +73 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Consciousness Science Underdetermined: A short history of endless debates [PDF]

, 2019
Consciousness scientists have not reached consensus on two of the most central questions in their field: first, on whether consciousness overflows reportability; second, on the physical basis of consciousness.
Michel, Matthias
core  

An Interpretation of the Continuous Adaptation of the Self/Environment Process [PDF]

, 2010
Insights into the nondual relationship of organism and environment and their processual nature have resulted in numerous efforts at understanding human behavior and motivation from a holistic and contextual perspective. Meadian social
Francovich, Chris
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Historical responsibility, historical consciousness, ideology [PDF]

, 2016
Historical responsibility is regarded as a kind of social responsibility, it is interpreted in two meanings: a narrow one and a broad one. In a broad meaning – historical responsibility is the responsibility towards history.
Krivonosova, Ye. E., Rudkovskiy, E. I., Кривоносова, Е. Э., Рудковский, Э. И.   +3 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Intercultural Historical Thinking and its Sense in the History of Civilization

História da Historiografia
This article explores the importance of intercultural historical thinking in the age of globalization and its significance to the historical study of civilization. The article points out that in the context of globalization, human beings are still faced
Yu Peiyun
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source