Results 101 to 110 of about 1,579,238 (304)
, 2010 Book synopsis: Walsingham was medieval England's most important shrine to the Virgin Mary and a popular pilgrimage site. Following its modern revival it is also well known today. For nearly a thousand years, it has been the subject of, or referred to in,
Janes, Dominic
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Al-TahrirThis study examines the intellectual and historical development of da’wah and Islamization in Nusantara, emphasizing key scholarly contributions, academic trends, and influential periods.
Arik Dwijayanto, Muhammad Choirin
doaj +1 more source
Beyond a historicism without subject: Agency and the elusive genealogies of state sovereignty
Cogent Social Sciences, 2015 This article seeks to account for the theoretical contributions of poststructuralism to the issues of social and historical change in international relations.
Thierry Lapointe
doaj +1 more source
Approaches to monetary policy revisited - lessons from the crisis, 6th ECB Central Banking Conference, 18-19 November 2010 [PDF]
This volume contains a collection of papers, commentaries and speeches that review the strategic and operational decisions taken by the central banks to combat the crisis and that reflect on the lessons for the future.
Christian Thimann +2 more
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Shakespeare and Language [PDF]
, 2010 Written by a team of leading international scholars, this Companion is designed to illuminate Shakespeare's works through discussion of the key topics of Shakespeare studies.
Hope, Jonathan
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source