Results 71 to 80 of about 2,002,135 (290)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Civic Culture in Western and Eastern Europe [PDF]
, 2006 This paper examines the nature of civic culture and the strength of civic attitudes in postcommunist and western countries. In particular, it seeks to explore the internal consistency and durability of civic culture using World Values Survey and European
Janmaat, Germ
core +4 more sources
„Jen je škoda, že víme, jak to s Husem dopadlo.“ Šestisté výročí upálení Jana Husa v české vzpomínkové kultuře || "It's a shame we know what happened to Hus." The six hundred years' anniversary of the death of Jan Hus in the Czech memory culture [PDF]
Historie - Otázky - Problémy, 2018 The text explores the portrayal of Jan Hus in the context of the 600th anniversary of his death, which was commemorated in the year 2015. The author analyses different media used for commemoration of Jan Hus from the perspective of Memory Studies.
Kateřina Sixtová
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The untapped potential of plant thin cell layers [PDF]
, 2015 Thin cell layers (TCLs), which contain a small number of cells or tissues, are explants excised from different organs (stems, leaves, roots, inflorescences, flowers, cotyledons, hypocotyls/epicotyls, and embryos).
Botero Giraldo +15 more
core +1 more source
Heritage ScienceThe 35 wooden coffin paintings from the Tubo period of the Tang Dynasty, housed in the collection of Qinghai Tibetan Medicine Cultural Museum, are valuable materials for studying Tubo culture.
Yanli Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Indigenous society and immigrants : tourism and retailing in Lijiang, China, a World Heritage city. [PDF]
, 2003 This paper examines the present state of commercial use of historical buildings, details of business categories, and descriptions of items on sale in the shops in the old town of Lijiang, China in order to investigate the problems of cultural-tourism ...
Yamamura, Takayoshi
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source