Results 71 to 80 of about 349,501 (319)

Digital technology in mathematics education: Why it works (or doesn't) [PDF]

open access: yes, 2012
The integration of digital technology confronts teachers, educators and researchers with many questions. What is the potential of ICT for learning and teaching, and which factors are decisive in making it work in the mathematics classroom? To investigate
Drijvers, Paul   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Transformation of Russia’s Image in Turkish History Textbooks in Context of State Historical Policy during Cold War (1945–1991)

open access: yesНаучный диалог
This study examines how Turkey’s external and internal political orientations during the Cold War (1945–1991) shaped the perception of Soviet Russia and Russia in general, as well as how this process was reflected in school history textbooks.
A. Çelik, H. Bingöl
doaj   +1 more source

Kansas State Historical Society Annual Report, 2013

open access: yes, 2013
Covers Fiscal Year 2013 The Kansas State Historical Society, Inc., doing business as the Kansas Historical Foundation, is an IRS determined 501(c)(3) non-profit and serves as the fund raising, fund management, membership, and retail organization for the ...
Kansas State Historical Society
core  

Developing an understanding of the Kanadier Mennonite and implications for education [PDF]

open access: yes, 2000
vii, 158 leaves ; 29 cm. --The project focuses on a unique migrant population in Horizon School Division called the Kanadier Mennonites. The Kanadier Mennonites who depart Mexico and other Latin American countries present a number of educational ...
Gilmore, Cheryl Anne   +1 more
core  

Kansas State Historical Society News Releases, 2021

open access: yes, 2021
This internet resource contains news releases issued throughout the yearKansas Archeology Training Program Field School to Be Held in Shawnee County: Brown v Board of Education National Historic Site June 4-20, 2021 -- REVISED: Kansas Historical ...
Kansas State Historical Society
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Kansas State Historical Society Annual Report, 2012

open access: yes, 2012
Covers Fiscal Year 2011 The Kansas State Historical Society, Inc., doing business as the Kansas Historical Foundation, is an IRS determined 501(c)(3) non-profit and serves as the fund raising, fund management, membership, and retail organization for the ...
Kansas State Historical Society
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Historical education of primary school children: from theory to practice [PDF]

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки
The relevance of the problem of historical education in primary school is determined by the need for younger students to develop a sustained interest in history, awareness of the importance of their own cultural and historical identity.
Irina V. Verkhovykh   +2 more
doaj   +1 more source

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