Results 51 to 60 of about 191,461 (306)
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Benchmarking large language models for geolocating colonial Virginia land grants
Journal of Spatial Information ScienceVirginia's seventeenth- and eighteenth-century land patents survive primarily as narrative metes-and-bounds descriptions, limiting spatial analysis. This study systematically evaluates current-generation large language models (LLMs) in converting these ...
Ryan Mioduski
doaj +1 more source
Polish Cartographical Review, 2019 The aim of the author is to present the methodology of reconstruction of the Old-Polish transport network as exemplified by the historic Lublin Voivodship.
Zawadzki Mateusz
doaj +1 more source
Historical geocoding assistant
SoftwareX, 2021 The growing use of geographic information systems (GIS) and geographical analyses in different areas of the digital humanities highlights the need for geocoding, i.e. assigning geographic coordinates to records in a dataset.
Adam Mertel +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Polish Cartographical Review, 2016 The aim of the author of this article is to present cartographic visualizations designed for an international tourist project Shtetl Routes. The methodology consists of the study of early topographic maps, field studies, GIS analyses and 3D modelling. 63
Kuna Jakub
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Machine-Learning-Enhanced Procedural Modeling for 4D Historical Cities Reconstruction
Remote Sensing, 2023 The generation of 3D models depicting cities in the past holds great potential for documentation and educational purposes. However, it is often hindered by incomplete historical data and the specialized expertise required. To address these challenges, we
Beatrice Vaienti +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Transport Revolution on Land and Sea: Farming, Fishing, and Railways in Great Britain, 1840-1914
HoST, 2018 The introduction and expansion of rapid rail transportation in Great Britain helped transform sea fishing and make fresh fish a new commodity of mass consumption.
Schwartz Robert M.
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source